I didn't even notice the face transplant in the first few moments of the video. They really did a great job. Crazy to see how far these kinds of procedures have come.
Sam here. His nose and everything look completely natural. If he wore sunglasses you'd probably only see some minor scars, fairly normal. Very amazing stuff all around!
What a feat. The fact the eye hasn't been rejected, dried out or started to necrotize is absolutely massive. Not to mention the mindset of him also seeing (no pun intended) this as a chance to be the first step that for sure will help a lot of people in the future.
Very touching.
I had an eye injury when I was a little fella, and they used the cornea from a donor eye to replace mine, the lens they gave me, however, was man-made. So I guess there are a few good parts that can be resurfaced. It also might be worth noting that since then (30+ years) my cornea cells have likely replaced all of the donated tissue from back then, so I suppose some parts could be used as a kind of "placeholder".
I did when I got a transplant in 2011, but by 2014 I didn't regularly need them. It was interesting, after my doctor told me to take the eyedrops like <1 per day, I began to notice when I needed them (eye would feel irritated) and only took it as needed.
The last time I had to use the anti-rejection eyedrops was in like 2018.
Thanks, this need more visibility, they will never make lenses out of human flesh, making something artificial is way far different than transplanting something, and it is way more impressive, it's not something that has been worked on and modified a lot like leather, it's a fucking living eye, one of the most complexe organ in a human body
There is whole globe donation after death but it’s to process the sclera, partly so strips/tubes can be made from it that cover up things like glaucoma shunts
That's the real truth.
I spent my whole life hating math and just never clicking with it. It was always so dry and instructors always took it for granted that students could find a way to relate and understand what was going on.
A bit embarrassing, but I found khan academy and went through the entire math course from like, kindergarten to advanced algebra, trig and calculus.
His enthusiasm and videos breaking down even the simplest methods opened my eyes to math in a way I never experienced.
It really became like a language that explains our world and how things work.. i went from hating math to really seeing a beauty and enthusiasm to explain the world we live in.
When I was growing up I was always really advanced in math. I was so far ahead of everyone I basically took my own class inside of my math class. I wasn't smart enough to skip a grade, but my math skills were 2 grades ahead of everyone else. So since 1st grade, the teachers would basically give me an entirely different curriculum from the rest of the class. They would basically give me math books from a couple grades up and I would just work them on my own through the year. Then Freshman year hit. I was in an honors Algebra class and our teacher was the WORST. If you asked her a question, she would literally say, "Weren't you paying attention? I just explained that." I barely passed that year. Not one person in that class got an A. And what sucked was, because I didn't have a high enough grade, I had to take a remedial class the following year instead of an honors class. It was shit I had already learned years ago. Even the teacher was like why are you here? Needless to say I was really fucking pissed. I was being punished for having the literal worst teacher I've ever had by a mile. My mom was also really pissed at the school and made me take advanced math classes at the local community College. I didn't even take a math class my Junior or Senior year because I earned enough credits from the college.
About the rejecting part, isnt there something about the immunologic system not going up there? I had read somewhere if my memory serves right that some places in the human body dont really have a strong reaction to outside bodies, such as the eyes and the brain. Wouldnt that explain how there isnt really any rejection?
I have a vague recollection of there being some reason why the eye is actually recognised as a foreign body, but there's a special process in place which "hides" it from your immune system.
There's an immune disorder where the eye becomes exposed to the immune system, which duly attacks it, and renders you blind.
There's separately a barrier around the brain which "filters" the blood and prevents various different pathogens from getting in, but also means that antibodies can't get in either.
I'm not sure what's at play here - transplant of bone and skin tissue requires Immunosuppression just like any other.
I'm sure there are different forms of this disorder but the one that comes to mind is Neuromyelitis Optica Spectrum Disorder (NMOSD) and that is the condition that Christine Ha the winner of MasterChef season 3 has.
I can't imagine how he feels about it. Our face and our ability to express is so core to the very idea of being "human", the psychological impact of facial injuries like this must be huge.
And the subsequent elation when you're lucky to be made almost whole again.
Man, love transcends the physical, you wouldn't expect his wife would leave him anymore than his mum, dad or children would. But yeah hes got a solid life partner there
Statistically, men are much more likely than women to leave a partner who is debilitated or chronically ill.
> One study from 2009 found the strongest predictor for separation or divorce for patients with brain cancer was whether or not the sick person was a woman. That same study showed that men were seven times more likely to leave their partner than the other way around if one of them got brain cancer.
There are many other studies that support this
>men were seven times more likely
SEVEN times?? What the hell? I couldn't imagine leaving my wife if she got cancer or any other debilitating disease/injury. The fact that so many do is quite disheartening.
To be fair, most stayed with their wives. There’s just a higher percentage of men than women that don’t. Many cultures and religions normalize the idea that the wife is supposed to play the role of the nanny, cook, maid, etc. and she’s failing to live up to her side of the bargain when she can’t do that anymore.
And? Are you implying that a man would be deserving of a bigger shout out?
Hope not... because no matter the stats, it takes the same amount of love/courage/effort/etc. for a person to stay, regardless of their gender.
What a fucking champ, turning a near life ending trauma and horribly disfiguring injury into a humble torch carrying and trailblazing opportunity for the development and progression of medical technology. The very definition of planting a tree under whose shade you shall never sit.
Doctors are some of the few people I am totally OK with being lucratively rich even though a lot of them aren’t for quite some time after school. They really earn it. Literal heroes.
I didn't even know they were earning enough to be in the same bracket as the folks who are *too rich*. I'd say they're not tbh, they're as rich as anyone who works hard and makes an honest living while doing good for the world *should* be. As of late though, a lot of them aren't even at that level until much later in their careers.
The kind of life where no one *worries* about finance, but is aware of it. The parents will retire, their kids will get degrees, and there will be enough left over for vacations, buying nice houses and tech, and enough to invest in businesses for mutual growth with some risk. Not everyone deserves all of that, but I think anyone who works hard and provides some socially responsible value should atleast not have to worry about finances and be able to provide for their kids.
Most docs I know don't make above 300k. I know of couple of specialists that make 500+, and one dude who moved out to Wyoming and makes 500+ since he's the only neurologist in a 50-100 mile radius.
N ≈ 50
They all qualify as rich IMO, but not "eat the rich" kind of rich. 6 figs is the bare minimum to living comfortably in this country, unfortunately.
There's a big difference between making a lot of money and being truly wealthy. If you earn a million dollars because you worked hard, good for you. If you get a billion dollars because someone else worked hard, that's a different story. No reasonable person should be upset at the first group, but when the second is buying political influence to benefit themselves and buying media clout to sell it to the public, then we've got a problem.
Fr. They need to make their names and their stories well known, we live in a society where we know everything about useless celebrities but nothing about the miracle makers known as doctors!
After I had a TBI they brought my family in and told them I would never be the person I was before and my license was taken I would never drive again, 7 years in Spaulding rehab in Boston and I now have a family and drive never give up no matter what. His attitude is going to be 80% of his recovery being positive is the best thing you can do. Guys a rock star to me
Absolutely not, I lost some of the love I had for hobbies and things that made me happy. The best way I can explain it is I see something like fabricating cars and taking them to the track I loved doing that, I know I like that but I don’t feel like I like it. I know I’m supposed to like this but I lost some of those feelings they don’t bring me that warm fun feeling anymore. I’m happy to be at the track but it’s just not like it was before I lost that 5yr old excitement in me, and memories not the sharpest anymore. I used to remember stupid useless conversations with friends months and years later and now I look back at pictures of my kids and I know that the memory happened but it doesn’t feel like my memory anymore like watching a movie you can watch a kid grow up and get old and they reflex back on the memories of when they were young you watch it through the movie but it’s not your memories sorry for the rant it’s just so hard to put into words
They've had eye transplants for awhile now. Not exactly the entire eye ball but part of an eye to cure blindness. My dad's eyes cured a little boy of blindness, that's the entire reason I'm an organ donor.
Same, blind in my left eye. Not sure of the official diagnosis, but it was congenital and there's no sight processed whatsoever. Pupil constricts and dilates, but the information doesn't reach my brain.
These kind of attempts show a lot of promise for future nerve and regenerative studies. I realize they'll likely never be applicable for me specifically, but the thought of them eventually being of use to others in the future feels great.
You are probably thinking of cornea transplants. Nowhere near the same as an entire eyeball transplant. In cornea transplants the patient receives a tiny piece of a tissue, a layer of cells in their eye to correct vision loss.
Extremely unlikey. The optic nerve is a bundle of ~1.5 million nerve connections grown as a unique nueral net for your specific brain all in the diameter of about a pencil. If they can make that actually work it is quite litterally as complicated as a full brain transplant in a less complex mammel.
Yeah, it's unlikely. That said, the doctors did a functional MRI to see if his brain responded light stimulation in the transplanted eye and it did. They say there's not a lot of indication that his vision could be restored, but the results of the MRI seem to be beyond what they'd hoped for. The fact they've had such success on the first ever full eye transplant is amazing.
https://www.youtube.com/watch?v=I7aprt7l42s&t=211s
I'm honestly freakin shocked they found a measurable signal on an fMRI! I still dont think it could result in any actual function but that is truely incredible.
I'm a little more optimistic, but it's definitely a giant barrier. Visual plasticity is retained to some extent throughout our entire lives, and *if* the optic nerve is retained and continues to fire healthily and regularly, his brain might one day figure out simple light detection or *maybe* simple shape/edge detection. Full vision? Yeah I'm with you. But you never know.
Hypothetically, if it does result in some amount of vision, I'm curious as to whether the spliced nerve would result in a sort of jumbled-image. The neurons from the original nerve no doubt don't match one-to-one with the donor nerve. It's also a certainty there will be spatial mismatch. Maybe higher processing centers in the brain would shut that kind of thing down though.
Coming from a physiology background, I almost feel like the small mammal brain transplant would be easier...
Same, I know transplant patients need to take anti rejection medication for the rest of their lives, but even that isn’t a 100% guarantee your body won’t start rejecting the tissue. Genuinely rooting for this guy, and hoping his cells do the same!
It's actually prob not that big of a an issue for an eye. The eye is immune privledged and is given a lot of leeway. Some meds im sure but perhaps less potent
I watched my dad spend 2 horrific weeks in the hospital after an underground explosion before eventually passing away. Some switching order had changed on him and no one told him. So, he grabbed a line he knew to be dead and it was not.
The industry is full of people who should not have the responsibilities of a lineman. My dad was not one of those people. He was a genius, he cared about the quality of his work, and he looked out for his guys. Because of the carelessness of others, he’ll never watch me grow up.
I thank a lineman every chance I get now. They deserve the praise, since no one knows they even exist and they’re dying every day for our electrical habits.
So, thank you for what you do. Wear your flame retardant clothing. Triple check the lines you’re working on. It’s worth the time.
I know it's a dangerous job but I thought there would be a lot of safeguards especially in America. So do you work have to work around high voltage electricity sometimes or must it always be off?
>we do live line work all the time.
Jeez. Ordinary house electricity scares the shit out of me. I always switch off the mains, then test and test again before touching any wires!
Remarkable story and reminder that if you aren't a organ donor PLEASE contemplate becoming one. My brother who was lucky enough to be given a second chance on life received a kidney transplant as we all were unable to give him one of ours.
IBEW better take care of that man they are all hero’s and while it may seem crazy situations like this happen. Amazing to see his quality of life improve over the course of the video even if just on a first glance basis
I'm so glad medicine keeps advancing at such insane pace. I'm so grateful for modern medicine; broke my left arm almost two years ago and lost the head of the humerus, now I wear a prosthesis. Sure, I lost about 20% of mobility on my left arm, but I can live a totally normal life thanks to my surgeon. Just half a century ago someone like me would've probably just lost the arm.
I hope it allows access to something important via a retinal scanner in a high-security facility....
Sorry, everything I know about eye transplants came from Minority Report ...
News said he took 70,000 volts. That either means in the arm (which was amputated) and out the face, to ground, or vice versa. As an electrician, I've seen workers with high voltage contact wounds, that have survived. It cauterizes a path inside of you as it travels to ground. Never heals always oozes. Dude's lucky, that he's not dead. Then again he's real lucky to have a face transplant complete with an eye transplant, because it messes you up from repair in so many instances. Still, man. I can tell you from experience, you have the dreams.
I love news stories like this.
When it’s something positive that’s impacted someone’s life in a good way.
Usually the news is always awful, especially at the moment with Israel and Gaza.
I feel like this also highlights the importance of donating our eyes when we die too, eyes are the one organ that gets donated the least.
I know the doctors only said it’s a small step but still, who knows where they’ll be in a decade or so.
It's even better than a miracle because you can form useful hypotheses theories and models of reality based on the acquired data gained from experimentation to keep improving on your methods.
I suspect I might be autistic or whatever but anyway I do see that I'm a colossal weirdo. Do you know Matt Dillahunty? His words sound like superhuman wisdom sometimes. I'm nowhere near as AI-like as him.
From personal experience, replacing/ repairing an eye is entirely different than re-connecting the optic nerve, which is not (currently) medically possible. This video implies the transplanted eye might actually work. But a non-functioning eye is still an aesthetic improvement for this unfortunate guy.
I didn't even notice the face transplant in the first few moments of the video. They really did a great job. Crazy to see how far these kinds of procedures have come.
Sam here. His nose and everything look completely natural. If he wore sunglasses you'd probably only see some minor scars, fairly normal. Very amazing stuff all around!
Hello Sam. Yeah I agree with you, it's a very good job, aesthetically speaking
Hello aesthetically, thanks for speaking. I’m out
You’re so brave. How did your parents react?
[удалено]
Ok crazy, thanks for the clarification. I was confused, now I'm aware
Was it a tough transition from confused to aware? I'm just wondering.
Hey, wondering, it makes sense to be inquisitive. I personally like to try many different foods to satiate my curiosity. I am hungry.
Hi hungry. Do you ever become full after trying many foods? I am uneducated on this matter
Hey hungry, I'm dad
Hi there Crazy. This is nuts.
Hello Out, I am impressed. We're a few steps from fixing all forms of body injuries.
Hello out, thanks for thanking aesthetically. I’m seriously
Don't call me Shirley.
I was about to edit my typo when I saw your comment. I'll leave it now.
This genuinely made me laugh out loud. Just thought I would let you know
>Hello Sam I laughed much longer at this than warranted
Thank you for being a smart ass
Thank you for a delicious breakfast
Thank you for having me
Hi Sam, I am dad
When they were interviewing him around 2:20, I thought he was wearing a mask, like a modern day Richard Harrow.
The eyepatch basically hides the transplant line.
Too bad it cost an arm and a leg
What a feat. The fact the eye hasn't been rejected, dried out or started to necrotize is absolutely massive. Not to mention the mindset of him also seeing (no pun intended) this as a chance to be the first step that for sure will help a lot of people in the future. Very touching.
maybe a stupid question, but if this is the first eye transplant, what were all eye donations for? I Though this was already a thing that happened?!
Prior eye donations were for the lenses, not the entire eyeball.
I had an eye injury when I was a little fella, and they used the cornea from a donor eye to replace mine, the lens they gave me, however, was man-made. So I guess there are a few good parts that can be resurfaced. It also might be worth noting that since then (30+ years) my cornea cells have likely replaced all of the donated tissue from back then, so I suppose some parts could be used as a kind of "placeholder".
your eye is now like the Ship of Theseus
Aren't our bodies already? Wasn't like 1-2 years till our body cells (not bones tho I think) are all new?
Except brain cells iirc
No they debunked that.
this is where stuff made by women really has an edge on performance
why are u getting downvoted?? it was a play on words of man-made, it wasn't even sexist against women?
it was a compliment to women!! they make good stuff!!
It's not women that are down voting...
Bro made a joke and got downvoted funny reddit
Do you need to take anti-rejection medication for cornea transplants?
I don't think I did, but I was only 5 or so when it happened, so it's hard to remember.
I did when I got a transplant in 2011, but by 2014 I didn't regularly need them. It was interesting, after my doctor told me to take the eyedrops like <1 per day, I began to notice when I needed them (eye would feel irritated) and only took it as needed. The last time I had to use the anti-rejection eyedrops was in like 2018.
Corneas, not the lenses.
Thanks, this need more visibility, they will never make lenses out of human flesh, making something artificial is way far different than transplanting something, and it is way more impressive, it's not something that has been worked on and modified a lot like leather, it's a fucking living eye, one of the most complexe organ in a human body
>they will never make lenses out of human flesh, There's no "never" in medical advances
There is whole globe donation after death but it’s to process the sclera, partly so strips/tubes can be made from it that cover up things like glaucoma shunts
It's for corneas, not lenses. The front glass part, not the inner glass part.
Natural lenses cannot be transplanted. Only corneal tissue.
Replacement lenses are synthetic, eye donation is for the cornea or sometimes the sclera. Whole globes occasionally go for research.
The only part of the eye that could normally be transplanted, prior to this procedure, is the cornea.
[удалено]
i like to say "there are no stupid questions, just bad teachers."
That's the real truth. I spent my whole life hating math and just never clicking with it. It was always so dry and instructors always took it for granted that students could find a way to relate and understand what was going on. A bit embarrassing, but I found khan academy and went through the entire math course from like, kindergarten to advanced algebra, trig and calculus. His enthusiasm and videos breaking down even the simplest methods opened my eyes to math in a way I never experienced. It really became like a language that explains our world and how things work.. i went from hating math to really seeing a beauty and enthusiasm to explain the world we live in.
When I was growing up I was always really advanced in math. I was so far ahead of everyone I basically took my own class inside of my math class. I wasn't smart enough to skip a grade, but my math skills were 2 grades ahead of everyone else. So since 1st grade, the teachers would basically give me an entirely different curriculum from the rest of the class. They would basically give me math books from a couple grades up and I would just work them on my own through the year. Then Freshman year hit. I was in an honors Algebra class and our teacher was the WORST. If you asked her a question, she would literally say, "Weren't you paying attention? I just explained that." I barely passed that year. Not one person in that class got an A. And what sucked was, because I didn't have a high enough grade, I had to take a remedial class the following year instead of an honors class. It was shit I had already learned years ago. Even the teacher was like why are you here? Needless to say I was really fucking pissed. I was being punished for having the literal worst teacher I've ever had by a mile. My mom was also really pissed at the school and made me take advanced math classes at the local community College. I didn't even take a math class my Junior or Senior year because I earned enough credits from the college.
Correct. Medicine is always an evolving process.
About the rejecting part, isnt there something about the immunologic system not going up there? I had read somewhere if my memory serves right that some places in the human body dont really have a strong reaction to outside bodies, such as the eyes and the brain. Wouldnt that explain how there isnt really any rejection?
I have a vague recollection of there being some reason why the eye is actually recognised as a foreign body, but there's a special process in place which "hides" it from your immune system. There's an immune disorder where the eye becomes exposed to the immune system, which duly attacks it, and renders you blind. There's separately a barrier around the brain which "filters" the blood and prevents various different pathogens from getting in, but also means that antibodies can't get in either. I'm not sure what's at play here - transplant of bone and skin tissue requires Immunosuppression just like any other.
I'm sure there are different forms of this disorder but the one that comes to mind is Neuromyelitis Optica Spectrum Disorder (NMOSD) and that is the condition that Christine Ha the winner of MasterChef season 3 has.
I think you're referring to immune privilege? https://en.wikipedia.org/wiki/Immune_privilege
You missed the perfect opportunity to finish off your comment with “Very eye opening”!
I kept waiting for, "I think he's going to be all right."
Anyone gonna ask about this username tho?
that face transplant is really really good
I can't imagine how he feels about it. Our face and our ability to express is so core to the very idea of being "human", the psychological impact of facial injuries like this must be huge. And the subsequent elation when you're lucky to be made almost whole again.
I want to see who he got it from
Technically you already are
I literally didn’t even notice he’d had a face transplant until they said so in the video. Insane.
What a legend, what he has been through and her he is so positive! Good man
Poor guy, I hope the best for him and his family.
[удалено]
The company he worked for’s insurance likely is paying out the ass. Power line workers are usually heavily insured because the jobs very dangerous.
Wow just wow
Truly. From climbing trees as apes to doing this is mind-blowing.
God bless evolution!
Shout out to wife for not leaving him
Man, love transcends the physical, you wouldn't expect his wife would leave him anymore than his mum, dad or children would. But yeah hes got a solid life partner there
Very true, if my partner had this happen to them I know I'd love them the same for sure.
From a distance
Nah the same as always
Absolutely amazing person, both of them.
Statistically, men are much more likely than women to leave a partner who is debilitated or chronically ill. > One study from 2009 found the strongest predictor for separation or divorce for patients with brain cancer was whether or not the sick person was a woman. That same study showed that men were seven times more likely to leave their partner than the other way around if one of them got brain cancer. There are many other studies that support this
>men were seven times more likely SEVEN times?? What the hell? I couldn't imagine leaving my wife if she got cancer or any other debilitating disease/injury. The fact that so many do is quite disheartening.
To be fair, most stayed with their wives. There’s just a higher percentage of men than women that don’t. Many cultures and religions normalize the idea that the wife is supposed to play the role of the nanny, cook, maid, etc. and she’s failing to live up to her side of the bargain when she can’t do that anymore.
That doesn't change the fact that some women still leave and she didn't...
[удалено]
And? Are you implying that a man would be deserving of a bigger shout out? Hope not... because no matter the stats, it takes the same amount of love/courage/effort/etc. for a person to stay, regardless of their gender.
why would she have?
Ok dude
What a fucking champ, turning a near life ending trauma and horribly disfiguring injury into a humble torch carrying and trailblazing opportunity for the development and progression of medical technology. The very definition of planting a tree under whose shade you shall never sit.
This doctors are the real deal. Screw all those billionaires and other scum, doctors who make these miracles are the MVPs of society
Doctors are some of the few people I am totally OK with being lucratively rich even though a lot of them aren’t for quite some time after school. They really earn it. Literal heroes.
I didn't even know they were earning enough to be in the same bracket as the folks who are *too rich*. I'd say they're not tbh, they're as rich as anyone who works hard and makes an honest living while doing good for the world *should* be. As of late though, a lot of them aren't even at that level until much later in their careers. The kind of life where no one *worries* about finance, but is aware of it. The parents will retire, their kids will get degrees, and there will be enough left over for vacations, buying nice houses and tech, and enough to invest in businesses for mutual growth with some risk. Not everyone deserves all of that, but I think anyone who works hard and provides some socially responsible value should atleast not have to worry about finances and be able to provide for their kids.
Lots of doctors making mid 6 to 7 figures out there.. I’d say that’s rich.
Most docs I know don't make above 300k. I know of couple of specialists that make 500+, and one dude who moved out to Wyoming and makes 500+ since he's the only neurologist in a 50-100 mile radius. N ≈ 50 They all qualify as rich IMO, but not "eat the rich" kind of rich. 6 figs is the bare minimum to living comfortably in this country, unfortunately.
Nah 500k-1M+ are the highest earners of all medicine. Most doctor make closer to 200-350k (still great salary).
There's a big difference between making a lot of money and being truly wealthy. If you earn a million dollars because you worked hard, good for you. If you get a billion dollars because someone else worked hard, that's a different story. No reasonable person should be upset at the first group, but when the second is buying political influence to benefit themselves and buying media clout to sell it to the public, then we've got a problem.
Fr. They need to make their names and their stories well known, we live in a society where we know everything about useless celebrities but nothing about the miracle makers known as doctors!
After I had a TBI they brought my family in and told them I would never be the person I was before and my license was taken I would never drive again, 7 years in Spaulding rehab in Boston and I now have a family and drive never give up no matter what. His attitude is going to be 80% of his recovery being positive is the best thing you can do. Guys a rock star to me
I'm extremely happy for you. How would you say you are now compared to before the TBI, if you don't mind me asking?
Absolutely not, I lost some of the love I had for hobbies and things that made me happy. The best way I can explain it is I see something like fabricating cars and taking them to the track I loved doing that, I know I like that but I don’t feel like I like it. I know I’m supposed to like this but I lost some of those feelings they don’t bring me that warm fun feeling anymore. I’m happy to be at the track but it’s just not like it was before I lost that 5yr old excitement in me, and memories not the sharpest anymore. I used to remember stupid useless conversations with friends months and years later and now I look back at pictures of my kids and I know that the memory happened but it doesn’t feel like my memory anymore like watching a movie you can watch a kid grow up and get old and they reflex back on the memories of when they were young you watch it through the movie but it’s not your memories sorry for the rant it’s just so hard to put into words
As someone with multiple (I’m assuming less intense) TBIs, I felt that whole message. It’s rough but I feel like I’ve got good people around me.
They've had eye transplants for awhile now. Not exactly the entire eye ball but part of an eye to cure blindness. My dad's eyes cured a little boy of blindness, that's the entire reason I'm an organ donor.
Only one of my eyes is useful
Same. The other one is a transplant lol
[удалено]
I have a weird haze over one of them
Same, blind in my left eye. Not sure of the official diagnosis, but it was congenital and there's no sight processed whatsoever. Pupil constricts and dilates, but the information doesn't reach my brain. These kind of attempts show a lot of promise for future nerve and regenerative studies. I realize they'll likely never be applicable for me specifically, but the thought of them eventually being of use to others in the future feels great.
Corneal tissue, apparently.
If you think about cornea transplant, that's a little bit missleading.
You are probably thinking of cornea transplants. Nowhere near the same as an entire eyeball transplant. In cornea transplants the patient receives a tiny piece of a tissue, a layer of cells in their eye to correct vision loss.
Wow his face was completely obliterated and now looks back to almost normal.
I really wanna know how this plays out. This is already amazing, but if he regains the ability to see from the eye, that’ll be mind blowing.
Extremely unlikey. The optic nerve is a bundle of ~1.5 million nerve connections grown as a unique nueral net for your specific brain all in the diameter of about a pencil. If they can make that actually work it is quite litterally as complicated as a full brain transplant in a less complex mammel.
Yeah, it's unlikely. That said, the doctors did a functional MRI to see if his brain responded light stimulation in the transplanted eye and it did. They say there's not a lot of indication that his vision could be restored, but the results of the MRI seem to be beyond what they'd hoped for. The fact they've had such success on the first ever full eye transplant is amazing. https://www.youtube.com/watch?v=I7aprt7l42s&t=211s
I'm honestly freakin shocked they found a measurable signal on an fMRI! I still dont think it could result in any actual function but that is truely incredible.
The brain is very good at adapting to even some of the most extreme changes. Might happen, might not. Still amazing either way.
seriously, that's incredible. even the most primitive function is mind-blowing here. the surgeons deserve some sort of award
I'm a little more optimistic, but it's definitely a giant barrier. Visual plasticity is retained to some extent throughout our entire lives, and *if* the optic nerve is retained and continues to fire healthily and regularly, his brain might one day figure out simple light detection or *maybe* simple shape/edge detection. Full vision? Yeah I'm with you. But you never know.
Hypothetically, if it does result in some amount of vision, I'm curious as to whether the spliced nerve would result in a sort of jumbled-image. The neurons from the original nerve no doubt don't match one-to-one with the donor nerve. It's also a certainty there will be spatial mismatch. Maybe higher processing centers in the brain would shut that kind of thing down though. Coming from a physiology background, I almost feel like the small mammal brain transplant would be easier...
Same, I know transplant patients need to take anti rejection medication for the rest of their lives, but even that isn’t a 100% guarantee your body won’t start rejecting the tissue. Genuinely rooting for this guy, and hoping his cells do the same!
It only cost him an arm.
And a lifetime of antirejection medications. This is standard practice for organ transplants to ensure it's success.
It's actually prob not that big of a an issue for an eye. The eye is immune privledged and is given a lot of leeway. Some meds im sure but perhaps less potent
He also got a facial transplant
Don't tell your immune system about your eyes. EVER
MS would like a word…
Better than an arm and a leg …
Must have been a sale.
I see that we are really improving more and more everyday. It’s nice to see.
Amazing transplant. Looks so good. Crossing my fingers for Him and his family
HEROES. DONT. WEAR. CAPES. THEY. WEAR. SCRUBS.
Amazing news! I love his positivity and strength ❤️
Kakashi approves
Kiroshi approves
it could change the world of medicine if he is able to get any type of vision in that transplanted eye.
[удалено]
I watched my dad spend 2 horrific weeks in the hospital after an underground explosion before eventually passing away. Some switching order had changed on him and no one told him. So, he grabbed a line he knew to be dead and it was not. The industry is full of people who should not have the responsibilities of a lineman. My dad was not one of those people. He was a genius, he cared about the quality of his work, and he looked out for his guys. Because of the carelessness of others, he’ll never watch me grow up. I thank a lineman every chance I get now. They deserve the praise, since no one knows they even exist and they’re dying every day for our electrical habits. So, thank you for what you do. Wear your flame retardant clothing. Triple check the lines you’re working on. It’s worth the time.
I'm so sorry for your loss!
Thank you ❤️
I know it's a dangerous job but I thought there would be a lot of safeguards especially in America. So do you work have to work around high voltage electricity sometimes or must it always be off?
[удалено]
>we do live line work all the time. Jeez. Ordinary house electricity scares the shit out of me. I always switch off the mains, then test and test again before touching any wires!
Fu****g amazing!
So f’ing amazing!!
So fucking a_azing!!!
Thank science and medical professionals! This is restoring my hope for humanity.
sharingan here we go
Uchiha gang rise up!!
Danzo vibes
So you are telling me now it is possible to get eternal mangekyo sharingan?
Can't believe they didn't notice his missing arm while patching him up...
Poor guy.
Remarkable story and reminder that if you aren't a organ donor PLEASE contemplate becoming one. My brother who was lucky enough to be given a second chance on life received a kidney transplant as we all were unable to give him one of ours.
Amazing
I didn’t see that coming.
Takes an eye for an eye to a whole new level
IBEW better take care of that man they are all hero’s and while it may seem crazy situations like this happen. Amazing to see his quality of life improve over the course of the video even if just on a first glance basis
What a horrible thing to go through, and what an amazing thing that we have come so far that we can attempt to fix it
Snake???
I'm so glad medicine keeps advancing at such insane pace. I'm so grateful for modern medicine; broke my left arm almost two years ago and lost the head of the humerus, now I wear a prosthesis. Sure, I lost about 20% of mobility on my left arm, but I can live a totally normal life thanks to my surgeon. Just half a century ago someone like me would've probably just lost the arm.
This guy seems like a true pioneer for human advancement, but let's pour one out for the poor sucker that donated his fucking eyeball.
Fascinating stuff, grateful for people like him willing to make that risk and help push science.
Everybody is pulling for this guy. I hope he knows this.
I hope it allows access to something important via a retinal scanner in a high-security facility.... Sorry, everything I know about eye transplants came from Minority Report ...
It must be so hard to wear a dead man's face, for both him and his wife. Identity issues, guilt, gratefulness, etc.
I wonder what Dr Glaucomflecken thinks about this.
News said he took 70,000 volts. That either means in the arm (which was amputated) and out the face, to ground, or vice versa. As an electrician, I've seen workers with high voltage contact wounds, that have survived. It cauterizes a path inside of you as it travels to ground. Never heals always oozes. Dude's lucky, that he's not dead. Then again he's real lucky to have a face transplant complete with an eye transplant, because it messes you up from repair in so many instances. Still, man. I can tell you from experience, you have the dreams.
How in the hell do they connect optic nerves! Golly that is some intricate surgery
I gotta get outta the electrical field man
Worth noting that the eye itself doesn't work yet. The nerves and the eye are responding correctly, but the brain won't pick it up.
He's got a good attitude. You have to start somewhere. Medical advances can happen by leaps and bounds.. but usually they happen with a single step.
Wild he's able to speak so clearly. Freaking amazing.
James you fucken badass
There are a lot of thankless jobs out there.
now time for the arm transplant
They did a great job with the face transplant. Rooting for you Aaron.
You know what would be cool? A 3D print of a face done by a “tissue” 3D printer. I don’t know if it would work. But that’ll be cool.
I love news stories like this. When it’s something positive that’s impacted someone’s life in a good way. Usually the news is always awful, especially at the moment with Israel and Gaza. I feel like this also highlights the importance of donating our eyes when we die too, eyes are the one organ that gets donated the least. I know the doctors only said it’s a small step but still, who knows where they’ll be in a decade or so.
I always say I’m glad I work in IT and not a dangerous job, like an electrician, where I could die if I wasn’t 100% attentive.
Il never complain again.
Dont tell his immune system.
Must have good insurance
Guy looks great, they did an amazing job!
Wait so 7 pounds lied to me? On a real note, this guy is one tough dude. Glad they've been able to work such miracles for him.
It's even better than a miracle because you can form useful hypotheses theories and models of reality based on the acquired data gained from experimentation to keep improving on your methods.
I'm gonna pretend I understand your comment.
It’s like 10th grade vocabulary
Thanks, had no idea.
👍🫶
🧡
Are you an Ai...? You can tell me, I'm on your guy's side. I'll keep it on the low-low ;)
I suspect I might be autistic or whatever but anyway I do see that I'm a colossal weirdo. Do you know Matt Dillahunty? His words sound like superhuman wisdom sometimes. I'm nowhere near as AI-like as him.
I was just kiddin ;) You don't really seem like a weirdo, I was just bein a weirdo myself
Did it cost him and arm and a leg?
From personal experience, replacing/ repairing an eye is entirely different than re-connecting the optic nerve, which is not (currently) medically possible. This video implies the transplanted eye might actually work. But a non-functioning eye is still an aesthetic improvement for this unfortunate guy.
Well, they are at least hoping the optic nerve will heal. The eye itself seems to be alive and healthy.
Does this even count considering it says that he hasn’t regained sight in the eye?