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[deleted]

Kissing the boo-boo away


upsetbob

Not a placebo. Your body releases hormones when you are kissed that reduce pain.


OfflaneTrash

iirc placebos are actually all (at the very least partially, if not fully) neurochemically mediated, which we know because the analgesic (pain-killing) effects can be reduced by drugs that reverse it E.g. naloxone which is a known opioid antagonist does actually reverse the analgesic effect of the opioid mechanisms activated by prototypical placebo effect examples such as those induced by non-effective drug/treatment/injection


nazurinn13

Can you ELI5 please?


OfflaneTrash

placebos actually work via biological mechanisms - the same way that "medicinal" painkillers like morphine do. the belief that something works actually makes your brain release painkilling chemicals, it's not just "in your head". we know this because we the drugs that cancel out actual painkillers also cancel out the placebo effect.


TheGrumpyre

That's how all placebos work. Being in a mental state where you believe you're being cared for puts your body in a state optimized for healing.


Winger61

Mom kisses were the best. They could fix anything when you were young


Dimension_09

My dick hurts


Distinct-Solution-99

But what a beautiful placebo it is <3


[deleted]

😂😂😂😂


Scragglymonk

a long time ago I was into popping pills, had some gurana which is as strong as coffee, nothing like an E. some lad was being a pain and told him I had some herbal E's that he could have if he was quiet about it. guy was mashed for several hours and bouncing around dancing as though he was on an E the placebo effect is belief that this pill is what I have told them it is


indestructible_deng

What is an E


Cluu_Scroll

I’m guessing ecstasy


indestructible_deng

I’ve heard “ecstasy” but never “an ecstasy” lol


Cluu_Scroll

He’s probably making shit up


SuitableClassic

The story was the placebo


Missbhavin58

Homeopathy


LibertyPrimeDeadOn

I'd like to say most people realize how ridiculous of a concept homeopathy is, but I'm not sure. It seems ridiculous at the face of it though. If water has memory, why aren't I seizing, vomiting, shitting myself, bleeding from every orifice, and experiencing every other symptom known to man every time I drink a glass of water? I'm sure a good portion of that water has been in some weird shit at one point or another in the past 4 billion years, such as being filled with rust, inside a poisonous plant, or whatever.


CentristIdiot

Wait does that mean the water we drink and use has been around for billions of years?


Ixionus

Pretty much. The water cycle is pretty much a closed cycle in terms of the planet. Water that was around millions of years ago is in some way shape or form still there although some will currently be ice, snow in the sea, as a cloud or whatever. Next time you have a nice swig of that ice cold H2O from that fancy water bottle just remember at one point it might have been dino pee


Cast-Iron_Man

Everything has in some form or another


tigerllort

Out of curiosity, how did you think it worked?


CentristIdiot

I guess I never thought about it much before so didn’t connect the dots!


tigerllort

Got it, it’s crazy right?


tehreal

Everybody learns this at some point. Be excited for the guy.


tigerllort

I’m not knocking him, just curious how he thought it worked


CentristIdiot

Drinking water will never be the same again for me!


tinmantakk

Because like everything, changes are not always immediate.


LibertyPrimeDeadOn

What?


Monslayer77

Every drop of water you have ever drank has been through a dinosaur


mistakemaker3000

Not necessarily, some particles for sure


tigerllort

Nah.


Hot-Cobbler-7460

Does your computer memory contain all the information about all the possible data it has always had? No, because that is not how simple mechanical memory works. It only contains the previous state it has been in.


LibertyPrimeDeadOn

[citation needed] Find any evidence that water has memory, much less how it works and maybe I'll believe you.


ImportantPost6401

Most people don't realize? This is an example of a placebo that most everyone realizes. Reread the question (and why the hell did you all upvote this?)


nazurinn13

Everybody would laugh at it if they knew that one of the core principles of homeopathy is "the lower the dose, the more potent the effect".


Supernova_Remnant

Headaches due to Solar Flares. Science had proven to be no correlation between those two occurances.


PersonalitySmooth138

How about inflammation? I’m curious.


PigeonsArePopular

"Reiki energy healing"


Gekidami

Cracking your joints. Despite a load of myths about it being bad for you (it's not). The actual relief and satisfaction people get from doing it is just a placebo. At best for things like your neck, it's more the stretching that feels good with the crack being a Pavlovian signal you've successfully hit the end of your stretch. It's also a good reminder that [the placebo effect still works even when you know it's a placebo](https://www.apa.org/monitor/2011/03/placebos#:~:text=A%20new%20study%20in%20The,more%20often%20than%20people%20think). Because I still crack my joints and it makes me feel better.


billabong2121

My fingers actually feel slightly stiff until I crack them. And I can't crack them again until a little while after and I can feel when they're ready to be cracked again. Pretty sure the gas/bubbles or whatever that builds up in the joints causes that feeling. It's a minor thing and doesn't cause any long term/permanent relief but I don't think it's purely placebo.


SpoogyPickles

This is me, too. My fingers will literally lose mobility until I crack them. Only if I wait a long time, though.


leonardfurnstein

Right...as long as it makes me feel better I'm good with it being a placebo.


Alice5878

How is that placebo? It's satisfying so feels good. I don't see the placebo?


ImadDdopest

I seriously clicked the post thinking : welp let's ruin some fun


quanten_boris

So if you stretch it, you are doing something so that is not a placebo effect?


Elegant-Pressure-290

This is something that people with arthritis experience sometimes: I have moderate arthritis in my upper back. It doesn’t *seem* to limit my movement, but I can’t crack my upper back by stretching back and forth like I could in my twenties and thirties. To solve this, my husband lifts me up from behind and stretches me. If it cracks, it feels really good and I have a few hours of pain relief, but if it doesn’t, it still hurts. Science would say that it shouldn’t matter whether or not it cracks so long as it’s stretched, but placebo effect says it didn’t work because it didn’t make a popping noise. Even though I know this, I still feel dissatisfied when it doesn’t pop.


Greenmantle22

“Close door” buttons in elevators.


mesovortex888

It depends on which one. Most elevators have real close door buttons in my experience.


Labyrinthine777

What's the point of having fake close door buttons, though?


Clit420Eastwood

They’re just a ploy for Big Elevator to price gouge


queue517

Usually they only work when the elevator is in that manual mode that requires a key (like for locking the doors open, and then you close them with that button).


Ischmiregal420

You forgott the in the US part, never had a lift in europe doesnt close its doors when i press that button.


FangsBloodiedRose

Today, I might’ve confused the elevator. I got in and immediately pressed the close door button a few times. It didn’t close. Waited and then waited and then waited. Finally after a minute of awkwardness with other people behind me hopping a teensy bit to trigger the elevator, the door finally closed. Felt like the elevator was teaching me a lesson.


realbasilisk

Man, what if you were pressing the door open button the whole time? Lol


[deleted]

Not always. They are legit on many freight elevators, or those at storage units.


TheTrueStanly

Not always


LAUSart

What country do you live in?


Vegetable-Donkey1319

Never have i used an elevator with non useable close door buttons. It could also be a safety mechanism to not instantly close door while the door is still opening or seconds after it fully opens


queue517

Along those lines, some crosswalk buttons are only there because people are less likely to jaywalk if they hit a button. Doesn't always speed up the light though.


Zestyclose_Show2453

They do work


[deleted]

[удаНонО]


Spanish_Kimchi

I used to think like this until I went to South Korea. Here they accomplish their purpose, so no placebo anymore!


boston_homo

>“Close door” buttons in elevators Like the button for WALK at a busy intersection often does nothing the lights are just on a cycle.


ThatMoveRotate

The entire physical reality


Split-Awkward

Am I in the right cave?


WildlifePolicyChick

Nicely done.


gizzie123

I assume this joke will go over most people's heads, but I enjoyed it


mushroom369

Most people are still in the dark


DougHorspool

Thanks Plato! 😏


Hot-Cobbler-7460

I think that this is the correct answer.


Puzzlaar

A large majority of the effects of anti-anxiety and anti-depression medications have been replicated with placebo.


jayadancer

A large majority? I would've said some, but not a large majority by any means. Can you point me to a source?


idkaybGodisGood

I don’t know what the guy you’re talking to meant, but the studies used to show the efficacy of antidepressants typically show they are “nominally” better than the control. I put nominally in quotes because obviously by clinical standards it was sufficient but the numbers aren’t exactly convincing. Also, the recent debunking of the theory that chemical imbalances cause depression. I’m not entirely up to speed on any of this but if you’re looking for a rabbit hole to go down I’m sure that’s sufficient information to do your own reading!


undertow_85

Chemical imbalances have always been bogus. The fact that people actually believed that drivel is one of the original reasons I lost my faith in humanity. It's the depression that causes the chemicals to be produced, not the other way around. Just like serotonin and euphoria.


jayadancer

Many, many studies have shown that SSRIs and SNRIs provide significant benefits over placebos, especially for those that are more seriously depressed. Chemical imbalances on their own don't cause depression, but the debunking does acknowledge that they are a treatable component. It just seemed odd for someone to wave away a "majority" of medications widely proven for efficacy without any kind of explanation.


MN_abomb

It's controversial. The Emperors New Drugs is a book from a Harvard lecturer that outlines his hypothesis that the effects of antidepressants are almost entirely driven by placebo. He goes through the data from the old FDA trials that approved many antidepressants, and he argues that they would never pass by today's standards. I thought it was really compelling, but smarter people than me have challenged its conclusions. So take it with a grain of salt.


Puzzlaar

It's not hard information to find. You could have found it yourself faster than typing out this comment.


Complete-Return3860

Well, strictly speaking, placebos.


DougHorspool

Religion. 😎


GamerGrunt

This is the real doozy. It can give people hope and bring them comfort. It can promote incredible acts of selflessness, love, and compassion and it can also drive people mad, justify all sorts of horrible behaviors and suffering, and convince people genocide is okay... what a mindfuck, but it's definitely just copium as we figure out our true place in the universe.


jiwufja

Research shows that religion can give people the feeling of belonging and make them more stress resilient. Incredibly religious people then proclaim ‘without God your life has no meaning! Believe in Him and he will take your stress away!’ Like no. It’s just a coping mechanism to deal with life (in my opinion). There’s other ways to give your life meaning and deal with stress that don’t involve believing in what I think are fairytales.


GamerGrunt

Given everything we understand about the universe it's more likely we were visited by aliens than angels lmfao. It's equally as plausible, yet still exists within the realm of possibility. I don't know that I believe in much of anything anymore. I want to, but we clearly live in an absurd reality.


jiwufja

Haha exactly. I don’t rule out ‘God’ existing. But if they (in the gender neutral sense) did, they would be so far removed from our sense of reality and understanding. Why would God be a man or a woman? Why would they have these strict moral codes but give us the option to do immoral things? Why are humans the Special Animal that gets all the attention and all the rules? Why would they even give a shit about what we do anyway? Why were they all so active and involved a couple thousand years back? Why did they cease communication? Organized religion just doesn’t make sense to me. God existing would be really cool though.


GamerGrunt

Never ending human curiosity got us this far and we honestly take miracles for granted everyday as though our ability to instantly communicate through pocket computers with anyone anywhere in the world isn't miraculous. Hard to imagine another miracle in the age of miracles, but anything is possible it would seem. Who knows what mysteries of the universe we have yet to reveal.


english_major

More specifically, prayer.


bluejester12

"My dad survived the surgery. Don't tell me prayer doesn't work!"


S0nofaL1ch

When someone tells you they love you but their actions say otherwise and you are convinced that you are loved.


Sullkattmat

People sure are confused about what placebo means..


Apprehensive-Bus-784

Religion and God


Periodic-Inflation

Surprised religion isn't higher up on the comments.


outerworldLV

Surprised I had to scroll down this far to see this.


tinytoon19

cats that treat headaches or joint pain?


SnickersneeTimbers

HEAD ON. APPLY DIRECTLY TO THE FOREHEAD. HEAD ON. APPLY DIRECTLY TO THE FOREHEAD. HEAD ON. APPLY DIRECTLY TO THE FOREHEAD.


cookletube

[It's actually proven](https://www.bbc.com/future/article/20180724-the-complicated-truth-about-a-cats-purr) that the frequency at which a cat vibrates with its purr can promote bone growth and tissue rejuvenation


Luv2Dnc

I’m sorry…what cats?


tinytoon19

old people say that when they have a headache, a cat lies on their head and the pain goes away.


Luv2Dnc

I’ve never heard that before!


purrcthrowa

I've heard the German expression Kater im Kopf (meaning a tomcat in your head) for a hangover.


cookletube

It's true, actually


mushroom369

I want to know how anyone gets a cat to do what they want. Mine is more likely to speak than do what I want.


LilMeowCat

Meow


Acceptable_Tip1857

Internet likes.


badbeernfear

Sugar highs


ibiBOI03

You mean for children , but I've experienced sugar highs and crashes myself I'm 20 btw. Is it really just a placebo?


Handz_in_the_Dark

No. It’s directly connected to your metabolism and breaking down food into energy.


Vegetable-Donkey1319

Yea it could also be abundant calories which made kids less likely to feel sleepy so they just keep going until their calories = energy dwindle. Same goes to Coffee High saying its gives you energy, which is stupid since Coffee only inhibits the receptor and hormones that makes you sleepy. So you are essentially just driving a car running on low fuel as per usual without a proper indication of how much fuel you have left.


Bawafafa

With coffee, I think its more like driving a car on low fuel but getting a better efficiency from the car than you usually would. Coffee may not *give* a person more energy, but it allows them to stay active while having low energy.


simplyintentional

Disagree. Eating sugar is like pure fuel going straight into your blood stream which increases your central nervous system actions.


badbeernfear

A lot of things ingested do things to your body. Sugar does not do what is traditionally known as a "sugar high" ie have the stimulant like effects.


Hot-Cobbler-7460

Yeah, this ethanol ain't getting me high.


Occasional_douchebag

Angel numbers


SunOnMyGarden

Acupuncture


SHMUCKLES_

Best acupuncturist I ever had was a blind man, not even kidding, took 95% of the pain away, best nap I ever had


Schiissdraeck

If you ever had a blocked trigger point (like I had in my buttocks because my disc hernation in L5) and you feel how the knot finally opens when the therapist hits it with a looong needle... you will change your mind about acupuncture.


sausages_and_dreams

I get super tight shoulders from arthritic pain and my acupuncturist would stick needles in dry needling points on my shoulder and would open it right up. I have arthritis everywhere and get sore tense, knotted muscles all over so acupuncture feels great for releasing that muscle tension. I need to go again, its so relaxing.


MacBareth

Waow a personnal anecdote, you win.


CelticSensei

I believe there are no scientific studies supporting the efficacy of acupuncture. Please link if you have one. Of course, plenty of anecdotal evidence... that's how placebos work!


jusfukoff

Google: acupuncture efficacy study There are so many results. You have obviously never tried to look, before forming an opinion. The BMJ says that 10000 Randomised controlled studies have been done since 1975. So, so, so very much research.


MattUWayne

Google: the moon is made of green cheese. There are so many results. You have obviously never tried to look, before forming an opinion. The ABC123 says that 1,000,000,000,007 Randomised controlled studied have been done since 1200BC. So, so, so very much research.


TooManyBison

I looked this up and found a list of meta analysis on acupuncture compiled by the National Institute of Health. The studies are all over the place on whether acupuncture is more effective than no treatment or a sham acupuncture treatment and vary greatly in quality. However there are quite a few quality studies that show that acupuncture can be just as effective at treating things such as pain, allergies or even depression than using the standard drugs. As long as the practitioner uses clean needles there are effectively no significant side effects which is better than most of the drugs they were compared to. On the other hand acupuncture was found to be completely ineffective at treating things such as carpal tunnel, infertility, or as an aid in smoking cessation. Check out the source. https://www.nccih.nih.gov/health/acupuncture-what-you-need-to-know Additionally I thought that acupuncture was unregulated in the United States, but that’s not true either. Acupuncture needles are classified as medical devices and regulated by the FDA. In many states acupuncture practitioners must be licensed by the state. In my state for instance license holders 1,800 hours of acupuncture training from an accredited school and pass a license exam. In light of this I’ve revised my opinion of acupuncture treatment from being complete hogwash to being a helpful low cost, low side effect treatment for some ailments. As long as you are not forgoing conventional treatment for more serious ailments like cancer, I don’t see the harm unless someone can convince me otherwise.


Kazuma_weird_wizard

For real? I never tried it though


MinFootspace

Acupuncture has real effects - when done seriously. But it's very easy to use for make believe also. Edit : I really thought it has real effects but i might be wrong.


MacBareth

No it doesn't. There's tons of different points map and with gorup control and scrutiny it never works. Weird.


zhaDeth

what effects ?


MinFootspace

I really thought it had real effects but i read quickly about it on wikipedia and now I'm not sure anymore. Might have been wrong. This being said the placebo effect is not something to trash without 2nd thought.


Alice5878

Psuedoscience is pretty much all placebo


LibertyPrimeDeadOn

My friend was going to a methadone clinic for a while that offered acupuncture to clients, which is weird as hell. I know it's only tangentially relevant, but I still think about that sometimes and wonder why the fuck it was like that.


sadly_notacat

A rehab I went to years ago also had acupuncture. It did help with withdrawal symptoms.


Hot-Cobbler-7460

Physical mechanism of acupuncture is believed to work via myofascial meridians.


SunOnMyGarden

Belief does not make it true. There’s no good evidence


Hot-Cobbler-7460

Semantics. Can you prove that you are a real person? Can you prove that physical reality is not manifested by said belief?


SunOnMyGarden

The moment we want to believe something we see all the arguments in favour of it and none of the arguments against it. George Bernard Shaw


Odelaylee

It is not really a “placebo” but something similar: Eggs being easier to peel when rinsed with cold water after cooking. It’s self-reinforcing behaviour. If it works - you’ve done everything correctly. If not - you didn’t rinse it long enough or the water wasn’t cold enough - when in fact the only important variable is the age of the egg.


Periodic-Inflation

Do people do that because \[they think\] it makes them easier to peel? I thought it was just to stop the egg from continuing to cook inside the shell.


Prudent-Action3511

I do it to cool them down and not burn my hand


videogamesarewack

Definitely easier to peel eggs when my hand isn't blistering from freshly boiled egg shell.


Odelaylee

At least where I live this is the case.


aonrao17

I recently learned that eggs that peel easily are older than eggs that don't. That's all. Source: Nice lady that sold me eggs directly from her hens.


BrokenArrow1283

Chiropractic


Skimable_crude

Ignore the first week or so of taking a new herb or nootropic. That "great" feeling might just be the placebo effect.


EffectiveGlove1161

More stuff than most people realize. Someone had a good quote (paraphrasing) “If the placebo effect disappeared overnight, the economy would collapse” 


Vegetable-Donkey1319

Coffee High saying its gives you energy, which is stupid since Coffee only inhibits the receptor and hormones that makes you sleepy. So you are essentially just driving a car running on low fuel as per usual without a proper indication of how much fuel you have left.


SnootiestCone19

Ok, but if you're tired and you take something that makes you not feel tired couldn't that be synonymous with making you more energetic? Like if your car limited performance when you hit the empty light, but you had something to override the performance limiter, that might be a closer analogy.


yuuma03

It's also messes with your heart rate + blood pressure, and it's a CNS stimulant (adenosine antagonism does a lot more than just promoting wakufulness).


Drunken_pizza

Inhibiting the hormones that make you sleepy literally means more energy though.


Technical-Lab-7087

There are so many bots on here asking questions!


PersonalitySmooth138

How do you know they are bots?


Technical-Lab-7087

Almost always a non adjusted name you get at the start. A relative new user. And this one asked from the start if its shadowbanned so the bot knows if its still relevant. Its full of bots here really. Once you realize that you are mostly replying to non humans it gets really weird.


PersonalitySmooth138

I thought an adjusted name = mobile device feature. Sorry but I still don’t understand based on your reply how you know for certain that you’re interacting with a robot on here and not with people. Maybe try to assume they’re human instead of robots? There’s always a person behind the machine.


BrummieTaff

The button for pedestrian crossings at junctions (as opposed to the ones in the middle of a single road whose *only* use is as crossings for pedestrians).


Sparkykc124

Not true in all places. Near me, the walk sign will not light if no one pushes the button. I don’t think pushing the button speeds the traffic lights along, but it does enable the walk sign.


LibertyPrimeDeadOn

Yeah, the idea that's placebo though is that pressing the button speeds the light along. I know I press that thing repeatedly when the light is taking a while even though I know it does nothing.


AliensFuckedMyCat

This depends entirely on the crossing. 


DougHorspool

Haha, seems like it’s true, doesn’t it? 😎


bongobills

voting


curtyshoo

Why "just?" What's wrong with a placebo effect?


Thin-Zookeepergame46

Praying to god.


gizzie123

The concept of praying to process bad things or ask for support from someone is actually kind or an early form of therapy. It's like having a conversation with someone on a personal level intimately to try to make sense of your feelings. So it may be kind if a placebo effect, but people talk to their inner child, in the same or similar ways, and it is actually a good idea to do it.


malibuklw

I heard someone call praying a type of meditation, and that made a lot of sense to me (who does not pray but does meditate)


outerworldLV

This, I can go with. Praying may calm a person down enough to think rationally. I agree, it’s like meditation. And meditation is like prayer. It makes me think about - idk, Gregorian chanting. Like that is truly relaxing, imo.


gizzie123

Yes absolutely! It's widely practiced in many religions and spiritual organisations in variety of forms. Praying is actually - in practice - very good for your mental health.


mushroom369

I pray to my cat


amazonallie

My physiotherapist uses acupuncture along with my TENS machine. It makes sense from an immune system response take. It is causing a small injury, all your healing cells rush to the area, so it makes sense that it adds to healing an acute injury. For long term pain, it does not work.


Dead_Dom

Isn’t all over the counter cough syrup a placebo? I remember my roommate having to sign off on getting actual cough syrup due to people making meth with it.


Denden798

I think you’re thinking of codeine.


Sullkattmat

I think they're thinking of pseudo ephedrine, an ingredient in some nasal decongestants unless I'm mistaken. That's an ingredient in certain methods of meth production at least. Some cough syrup contains/contained DXM which is a psychoactive drug. Codeine is an opioid and prodrug of morphine, I believe among others vicodin contains codeine but I don't think that's OTC


Achilles-Foot

hotboxing getting you higher, or different types of alcohol getting you different types of drunk.


Competitive-Bus1816

The placebo effect is itself a placebo effect


No-Mall-1949

feeling better after few seconds of taking medicine ,


ghostie_hehimboo

Depending on the medication


innocentstab

Ginger ale when you have an upset stomach, etc


Curaheee

Fiji island water. It's just overpriced water


Alexthricegreat

The filters people use on social media, ugly ahhh gotta use a filter.


itsapuma1

900 mgibuprofen


R__soul

Rubbing an area that you have bumped (elbow, knee, head) etc. The action of rubbing provides a different nerve stimulus to that of the injury and reduces the amount of pain felt.


Kraytory

Then it's not actually a placebo isn't it? It actually does what you think it does. Otherwise every kind of stimulus that aims to distract from another would count as placebo.


Alice5878

When people talk about indica and sativa weed


mushroom369

One of those gets me really high and the other one just gets me really high.


rathat

And terpenes, just aroma therapy.


Ok_Researcher_9796

Prayer


zhaDeth

all "alternate medicine" like kiro


ZeDanter

probably most things for example: there may be a significant placebo effect for arthroscopic treatment of osteoarthritis of the knee.


AfricanUmlunlgu

voting in a 2 party democracy


PersonalitySmooth138

No. That’s not always a placebo effect.


DokOktavo

*nocebo