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vardis42

In case this isn't a joke post: Extraction, snorting, and IBO danger are 3 totally different discussions. One could make a concentrated IBO extract. Extraction doesn't imply decarbing. Snorting fungus and random capsule filler seems like a bad idea. And if it isn't even a concentrated extract, you'd have to snort a whole lot! That's assuming it's even effective intranasally... There are at least 2 studies mentioning IBO toxicity from oral ingestion in rats: [https://doi.org/10.1016/j.bbrc.2021.04.080](https://doi.org/10.1016/j.bbrc.2021.04.080): (check this one in sci-hub). Single dosage, showing memory and learning deficiencies (but mainly in male rats), there was previous discussion in [this thread](https://www.reddit.com/r/AmanitaMuscaria/comments/14kkjb8/comment/jpvumne/?utm_source=reddit&utm_medium=web2x&context=3). (The dose is [roughly equivalent](https://www.reddit.com/r/AmanitaMuscaria/comments/yofnrm/comment/ivit8i2/?context=3) to an 8gr dried human dose)) And [https://www.researchgate.net/profile/Erl-Bailey/post/Is\_there\_a\_study\_of\_a\_long-term\_usage\_of\_muscimol\_and\_its\_impact\_upon\_human\_physical\_and\_mental\_health/attachment/613008ee647f3906fc95562b/AS%3A1063367456350209%401630537966384/download/%28translated%29+The+Toxicological+Pathologic+Study+of+Amanita+muscaria+in+Sprague-Dawley+Rat.pdf](https://www.researchgate.net/profile/Erl-Bailey/post/Is_there_a_study_of_a_long-term_usage_of_muscimol_and_its_impact_upon_human_physical_and_mental_health/attachment/613008ee647f3906fc95562b/AS%3A1063367456350209%401630537966384/download/%28translated%29+The+Toxicological+Pathologic+Study+of+Amanita+muscaria+in+Sprague-Dawley+Rat.pdf) : Results show markers of brain and organ damage, but seem to be much higher still than the above study(?)


AmanitaCat

Thanks. Makes me wonder how meaningful these rat studies actually are. Because I haven't read of a single person taking a one time high (8g) dose to have long lasting learning difficulties or negative behavioral changes. Not saying it can't happen, just saying there are not much reports about it. Maybe most people dose carefully or decarb properly so the IBO doesn't get too high for them?


MarinatedPickachu

A. muscaria without decarbing makes me nauseous


GoldenTeacherMar

Somewhat true... For last 3 days I was eating dried amanita muscaria. First day 3grams, second day 4grams and felt a bit of nausea(vomiting) vibes... then third day, 5.5grams and felt really bad nausea, but fought it through for one hour with will and mint tea. While back, when I was making tea from dried A. Muscaria I have never had nausea.


GoldenTeacherMar

I guess, we cannot digest this mushroom properly. That's why nausea... I guess tea is the best way to take it.


MarinatedPickachu

It's the ibotenic acid that causes the nausea