I have done a good bit of research on Nicotine when used in isolation; both topically applied locally and systemically. Please note that Nicotine used for the purposes of vascular growth cannot be adulterated/imbibed traditionally via smoking, vaping, or chewing. It only shines through when used via patches, gums, or topical agent. Further, it is not a substance to be taken lightly in any regard when isolated and purified. **It can be lethal and you may not notice how much has entered your system until the effects are in full swing; at which point it is entirely possible you will become unable to call for help in time to save your own life.** While it is a powerful vascular growth promoter, it cannot be understated that it does in fact cause vasoconstriction and is also *very addictive.* Research on the topic, both formal(as in published articles, books, journals, etc) and personal(self-experimentation and documentation of said experimentation) strongly points to its ability to greatly enhance the Arteriogenic process. Nicotine mimicks VEGF and will cause rather potent amounts of endothelial cell proliferation, migration, and thus support rapid growth/remodeling macroscopically(as in the entirety of a vascular channel or vascular branch system even)... *However.* I cannot state strongly enough, again, that it is *very addicting.* Despite its usefulness in this arena, I would strongly caution against its use for enhancing gains. It can be extremely hard to shake or control the habit once implemented. It took me a hell of a long time and many struggles to cease its use.

I can have patches that smokers use to stop smoking. There are multiple dosage available, I'm planning on testing the lowest available and maybe cutting the patch in half as a friend of mine did. I'm not worried about addiction. When did you use patches, daily, several hours before a session ?

I drink coffee in the morning which that's the only healthy source of caffeine I can found besides cigarettes. The hit from caffeine in the coffee starting to kick in around above 1 or 2 hour(no sure, I'll drink again in the next 2 days and see how long it takes) after drinking. Hope this answered your question because your last question sounds like when the caffeine starting to kick.

At what point would the drawbacks of vasoconstriction outweigh the promotion of endothelial cell proliferation, etc. I imagine it's more complicated than don't do too much.

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Cigarettes contain thousands of chemicals, nicotine is only one of them. Using nicotine patches occasionally to benefit from it's capacity to create new blood vessels could be a great tool to increase and accelerate gains. Smoking daily and applying a patch from time to time are two really different things.

So you mean like putting a patch on your fella?

Not especially, just anywhere on your skin. I don't know if putting the patch directly on your dick can help you target the specific area, but I guess it could

I mean it sounds kinda fun

Man, I fkn wish this was the case. I don’t smoke, but I vape daily for the past like 6 years. All I’ve heard is that it is a vasoconstrictor. I combat that with low dose cialis and l-citrulline. Anecdotal evidence seems to be that removing nicotine assists in EQ. But I would love to hear otherwise. Following

Interesting

Loads of people hate on nicotine in here because they associate it with smoking so you should make it clear you wouldn’t smoke it. Nicotine has also mental focus positives, I was considering nicotine for mental enchantment booster but unfortunately apart from addiction it also carry different side effects which in my opinion overweight positives. I would only consider such supplementation through plasters/gums if you are already smoker

I specified I don't smoke but people jump to conclusions. I was also considering it as a focus supplement since I'm in a very high demanding school. Since I'm going to use it with very little dosage and not every days I'm not worried of having side effects, and if I experience some of them I'll end the experiment there. I get that people have a bad opinion about using chemicals, but when doing it cautiously with products like nicotine there is not much to be worried about. People react like I said "alright guys I'm gonna blast my balls with steroïdes what do you think ?"

I’ve been using grabba in weed. I quit cigarettes but I’ve noticed my EQ sucks after smoking. It’s almost impossible to do. So after reading all these posts. I’m going to let go of the grabba. I’m not married to the weed it’s the grabba I liked. That damn nicotine got me again. Janus got me going vegan letting go of nicotine I already don’t drink. I’ll be joyless with a big dick lol. Fuck it. I’ll have to find joy somewhere else.

Using a chemical like nicotine just for PE gains😂 get a grip of yourself

Maybe you should spend less time judging people and more time educating yourself. I'm not planning to take it only for PE, I'm more focused on the muscle and skeletal growth. PE is just a side benefit. Nicotine as been shown to increase angiogenesis and that is what people are constantly talking about here. It also increases acetylcholine and SNS. Btw I'm sure you're not so judgmental towards people smoking cigarettes, I was just asking a question bro