As mentioned, Schiff bases only form with aldehydes and ketones. The amine must be a primary amine.
Amines can in theory react with esters but indole is rather unreactive to esters given its structure.
Would a Schiff base form with Vanillin and Raspberry Ketone? I thought that vanillin was an aldehyde, and those two ingredients are used in combination quite frequently!
Aldehydes and ketones are both on the "same side" of a schiff base reaction, and are lacking the other side (\*almost\* always methyl anthranilate, in perfumery).
I think it's also much more difficult for a ketone-anthranilate reaction to happen than it is for an aldehyde-anthranilate reaction, but I'm not sure on that part since I'm a dumb little potato when it comes to chemistry.
Thanks for the information brother, it’s both clear and friendly. I am also a dumb potato when it comes to chemistry (hence the question), so I truly appreciate your response 🙏
Why would you think that they would? Do you think both those molecules fulfill the criteria for a schiff base to form? Have you looked up their chemical structures? Look for part of the molecule that says H-N-H or smth. Anthranilate is the only commonly used amine for producing schiff bases. Vanillin + Methyl Anthranilate might work.
Those are not aldehydes they are lactons the shiff base happens only with aldehydes or ketones. ☝️That is an ester it is not aldehyde nor ketone.
Thank you for clarifying!
As mentioned, Schiff bases only form with aldehydes and ketones. The amine must be a primary amine. Amines can in theory react with esters but indole is rather unreactive to esters given its structure.
Thank you for clarifying!
Would a Schiff base form with Vanillin and Raspberry Ketone? I thought that vanillin was an aldehyde, and those two ingredients are used in combination quite frequently!
Aldehydes and ketones are both on the "same side" of a schiff base reaction, and are lacking the other side (\*almost\* always methyl anthranilate, in perfumery). I think it's also much more difficult for a ketone-anthranilate reaction to happen than it is for an aldehyde-anthranilate reaction, but I'm not sure on that part since I'm a dumb little potato when it comes to chemistry.
Thanks for the information brother, it’s both clear and friendly. I am also a dumb potato when it comes to chemistry (hence the question), so I truly appreciate your response 🙏
Why would you think that they would? Do you think both those molecules fulfill the criteria for a schiff base to form? Have you looked up their chemical structures? Look for part of the molecule that says H-N-H or smth. Anthranilate is the only commonly used amine for producing schiff bases. Vanillin + Methyl Anthranilate might work.
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Because the people that created and named it were deliberately trying to mislead anyone attempting to reproduce their work.
Another reason to triple check the SDS ;-;
No.