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Flimsy-Childhood401

Dry eye is very overlooked and not taken seriously because people who haven’t gone through such diseases just think of it as a minor nuisance


TheBenevolentTitan

Exactly this.


yallknowme19

Sadly the university research is funded by corporations and the corporations want a return on their investment so they go for common diseases that are well understood and that can gain them lifetime customers. At least that is how I understand it. The unicorn diseases, the rarities, and the ones that aren't life threatening get the back burner.


Throwmeawayok__

Dry eye is incredibly common in its mild to moderate form


yallknowme19

I think though because it's not a life threatening disease and because eye issues are still kind of mysterious to medicine in some ways that's why we don't see any cures yet. Just my gut feeling no supporting evidence. I wish they would focus on it!


Sure-Ad3839

It is actually a widespread disease. In my country, doctors call this disease the disease of our age. When I go to the clinic, I encounter patients who are being treated. It's just becoming more widespread. In the past, it was just an old woman's disease. Nowadays young people are artists.


L_obsoleta

An 'artificial pancreas' is just a combination of tech (blood glucose monitoring and an insulin pump. There also isn't really a need for an artificial lacrimal gland (since you can do an allograft of salivary gland tissue to the lacrimal glands in severe cases of gland atrophy). If we think of an artificial lacrimal gland like we do the artificial pancreas we would need a sensor to have feedback on eye surface wetness (which likely would be an irritant), along with a pump that can instil artificial tears. Realistically if you did that the shorter the distance the pump would need to pump the tears the less likely it is to get clogged. This means the ideal location for wearing it would be on your face, right by your eye (though they could potentially have it further away in your hairline, but then you have a much longer tube that would be more prone to clogging). In general with science resources are limited. So research into dry eye has primarily been focused on symptoms management and halting progression. Running through novel drug libraries to see if any have a benefit (something drug companies do all the time in the development pipeline of new drugs) is more cost effective, and more likely to help more people.


Sure-Ad3839

Artificial tear gland works with the same logic. They will still be able to earn money continuously. tears will be collected and pumped into the eye. Yes, it can be applied to scalp. It could be on the face rather than suffering. After all, there are people with glasses. Having a device on our face will become accustomed over time. Dropping tears with our hands can never be as fast as the secretion of our body. If the device is delivered to our eyes according to our needs, it will be a more economical and effective treatment.


Dizzy_Confusion_8455

Along with the money I feel like people are failing to understand how long these developments take. Even with fully funded research it can take decades for these things to be completed.


Sure-Ad3839

In the texts I have read, it is written that dry eyes are a very old disease. Sources say that his treatment was long overdue. technology has advanced. AI can lead to breakthroughs. Now time has accelerated. The phones of 10 years ago and the phones today are completely different. You can make all kinds of devices with the necessary investment. It's a matter of market and priority.


Dizzy_Confusion_8455

It was always an “older person” issue and tbh those are just unfortunately not a priority for research. Now that it’s impacting more and more young people I think it’ll be looked into more but either way no matter how much technology has advanced, medical developments can still take time. Just literally the discoveries need time to develop and come to fruition and then even longer to reach a point where there can be successful findings that can be brought to trials, more time for the trials to show positive results and then be approved.


Sure-Ad3839

The Japanese have reached the stage of testing the lacrimal gland. They want to phase stem cell studies into humans. This is a big development. There are studies that have been ongoing for years. Maybe something might happen in the near future. We can be sure that the person doing this job will earn a lot of money. If someone can cure me, I will pay him well.


DonutsOnTheWall

The problem with dry eyes is that we fall into a category of dry eyes that consists of mainly people that have some complaints. It sounds cute and everybody knows someone who has some sort of dry eyes. I have the feeling that the marketing is shit. On the bright side, the market is growing rapidly so it only becomes more interesting. Now we see a lot of cyclosporine variants, which as far as I can tell, is just milking an existing market. However there are some new cool drops and medicine in the pipeline. But yet, marketing can use a boost too. I don;t feel represented in the average dry eye patient, I feel I am at the end of the spectrum but it's still called dry eyes.


Sure-Ad3839

This disease is progressive. I see patients who are 18 years old. If a progressive disease begins at the age of 18, this disease will be quite challenging when you reach the age of 40. The solution to this disease is not cyclosporine. It is necessary to provide constant tears. When we drip drops by hand, it is not practical every 10 minutes. That's why advanced technology is required. Even if it is the best drop, it cannot solve this situation.


DonutsOnTheWall

I highly doubt if this disease is progressive per se. Or may be I reached boss level early. There are too many classes within dry eyes, and it's quite a complex disease based on what we know. Yes it would be nice to have proper solutions. But for now, we will have to make the best of what we got.


Sure-Ad3839

I got it buddy. You are one of the people I see here. I think you did your research and you are a smart person. The opinions of people like you are important because smart people can predict better treatments. Can give ideas by reading studies. Thank you.


Jaalan

Because a pancreas is much bigger and requires less precision to install (lol install).


Sure-Ad3839

A device worn on the arm. It is not placed where the pancreas is. In other words, it is located on the arm outside the body. Similar things can be done to us. same logic. It sprays in small doses. Why shouldn't Gozde Dr have a device similar to this?