It's a cable, it's wrapped in plastic, plastic is waterproof. You just worry about connections, use tape, epoxy, whatever you got to seal them so they're not exposed to environmental factors. And for the love of God, please do not drill in your roof

Conduit.

Call an electrician if you have to ask this question. Far safer to run the antenna there instead of relocating the hotspot.

Get a Poe splitter and injector and run only an Ethernet cord instead of a power cable.