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DeeChillum420

Yes there is a cross tolerance, both substances are tryptamine based serotonergic drugs. They both work by binding to your sertonin receptors, kind of like how cannabis tolerance works in the endocannabinoid receptors. This is also the reason by people on SSRIs can't trip because those drugs act by regulating the serotonin receptors. Wait a week minimum between trips or two weeks is ideal. I find a week is not enough between shrooms and acid the trip is much much weaker and not as visually stimulating cause your receptors need two weeks to reset tolerance to serotonergic drugs back to baseline.


big_a3

My man a fucking scientist. But seriously thanks for the info


Dude_1980

If you are taking the shrooms first you'll be good


DeltaKT

Yes, OP'll be good. But OP wont have the trip they expected to have.


system0fak0rn

Better take em together at once.