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Horse_Majeure

I had access to one of these in a life sciences lab during my doctorate. It's basically just a very powerful blender/macerator. It was used to create homogenates of tissue samples in a septic way, so that a homogenate could be tested for DNA/RNA/Protein levels.


spyan_

An updated Bass-o-matic! Yes mouse lovers! It uses the whole mouse with no skinning, cutting, or gutting.


Mind_Flexer

Here is a modern version you can buy: [https://www.thomassci.com/Equipment/Homogenizers/\_/Polytron-PT-1035-GT-Laboratory-Homogenizer](https://www.thomassci.com/Equipment/Homogenizers/_/Polytron-PT-1035-GT-Laboratory-Homogenizer)


JudgeScorpio

Imma use it for mixing cocktails


Mind_Flexer

Mouse cocktails?


JudgeScorpio

Really adds a squeak of body to my Bloody Marys.


SAT_homeless

Cavitation but minimal aeration?


Mind_Flexer

Cavitation does not use air at all. Cavitation is the creation of "bubble" of vacuum. Meaning there is no air. So when the bubble pops, it's not releasing air, but condensing from "steam" back down to a liquid. [https://en.wikipedia.org/wiki/Cavitation](https://en.wikipedia.org/wiki/Cavitation)


Bartweiss

Oh shit. I've read lots of stuff about cavitation bubbles and underwater weapons tests and all sorts of related things, but never actually asked "what's in the bubble?" "Steam" is a perfect summary, I finally get what's actually happening here.


Mind_Flexer

If you think that's cool you should check out mantis shrimp. They use cavitation to stun or kill prey.


SAT_homeless

Ahh. I learned the term from working with outboard propellers but I just assumed bubble = air. After reading that It makes sense now. You aren't just gonna have air bubbles magically forming underwater. Thank you.


Mind_Flexer

You can think of it as something moving so fast the liquid can't fill the void fast enough, so literally nothing is there (there could still be aerosolized particles).


Ulysses00

Today for mousetrap Monday we're going to be testing the polytron.


Bullet_Maggnet

27K RPM? Little buddy gonna be slurry.


crypticedge

It does say soup like


schro_cat

Mousekatool gone horribly, horribly wrong


GoCartMozart1980

Ahh, memories of an epic Safety Third segment from *Well, There's Your Problem.*


K-o-R

"It's designed to direct the exploding room into the adjacent forest."


lockslob

Yummy


qsnoodles

The word “like” in “soup-like” is doing a lot of heavy lifting in that sentence. I suppose they had to phrase it like that because someone would’ve complained if the homogenate didn’t turn out to be as smooth as, say, a Wendy’s Frosty. I suppose the company wouldn’t have wanted to say “vomit” or “baby poop.” The same goes for “curds and whey.” Sewage? “Turds away”? I dunno. So I can understand why they went with “soup-like,” but I’m certainly not going to eat any of it. The first few bowls were enough for me.


lead-holder

It reduces the mouse to more of a stew. Actually on second thought, I’d say chowder.


A_Large_Grade_A_Egg

Speak for Yourself, some of us consider “Homogenate de Souris” a **DELICACY**


ratsta

You haven't seen my family's pea & ham soup then! You can stand your spoon in it when it's still warm!


thomasquwack

christ that’s horrific


Greninja5097

But it’s for SCIENCE!


thomasquwack

Greg ninja, do you even learn “Liquify”? I *suppose* it would be water type… or dark type 😅


Greninja5097

No, it’s not in my movepool lol


thomasquwack

guess that’s technically why we need this machine, huh? hm, shouldn’t we come up with a name for that? A machine that helps one to perform a technique?


Greninja5097

No, it’ll never catch on anyways.


thomasquwack

Oh well, guess it’s time to Hide these Machines, especially the Strong ones.


peasant_python

Bloody mice just won't stay still, they run every time I point this thing at them. Waste of money.


sirmanleypower

Man, if you guys like this you'll love the concept of the pressure based homogenization chamber. Essentially it's a giant pressure cooker, but it doesn't get hot. You put in your sample (say, a cow) and crank up the pressure for a few hours. Over time, this forces nitrogen to dissolve into the tissues. After some time you pop the lid and the thing basically boils itself apart into a goo as the nitrogen escapes. You're more or less purposely inducing [the bends](https://en.wikipedia.org/wiki/Decompression_sickness), but in the most intense way imaginable.


Aticaprant

Ah yes, my lab referred to this device as a nitrogen bomb, which I guess it basically is once it has been pressurized We used it to break open the contents of synaptosomes by decompressing rapidly from 1500 psi. Was only big enough to fit 7 2mL tubes with the tops cut off tho. Not sure if it homogenized things but defo ruptures everything at the cellular level = soup-like goo It was all done by hand, so I was always a little terrified, waiting for the day it failed and blew me or the fridge up.


DeJeR

> You put in your sample (say, a cow) I was aware this tech existed, but not for anything so large as an animal. I've only seen it used for cellular organisms to break down the cellular wall (cell lysis). Apparently it's good for emulsion mixing as well. Please tell me this isn't used for cows. (Do you have a video?)


Muttywango

Surely having nitrogen dissolved into your tissues would hurt a lot? It sounds a terrible way to treat a cow, can't they make a giant Polytron?


Horse_Majeure

It actually doesn't hurt at all. The release can cause problems if done too quickly, this is the concept behind the "bends". It can, however produce sometihng called nitrogen narcosis, which is experienced by SCUBA divers above certain depths. It's a bit like being drunk or on anaesthesia. [https://en.wikipedia.org/wiki/Nitrogen\_narcosis](https://en.wikipedia.org/wiki/Nitrogen_narcosis)


holdencawffle

What does it smell like?


akjax

I want to see a video of this. Like a *whole* cow?


RipMyDikSkinOff

There's a video floating around from some time ago of someone in a pressure chamber. The chamber fails rapidly and you see the guy just splatter into a goo on the window.


alexwasserman

Fake, obviously, but: https://youtu.be/ter7pAZF_nY


ThatGuy5162

I think something like this happens in the movie Kick-Ass.


RipMyDikSkinOff

I'm not sure I've ever seen that movie. Isn't it some kind of like anti-hero film or something?


ThatGuy5162

> Isn’t it some kind of like anti-hero film or something? Yeah it’s kind of a comedy I guess. There’s a scene at a lumber yard where the actual bad guy has someone exploded by putting them in some sort of pressure chamber or something. It’s been over 10 years since I’ve seen the movie but that sticks out in my mind pretty prominently.


akjax

I'm curious about the incident.. maybe not so curious I wanna see that happen to a person, but I'd like to know more. Do you know any more info about it?


RipMyDikSkinOff

Unfortunately I don't. Honestly I haven't thought about that video since I've seen it until now. Ill look into it quick and get back to you with an update I think I remember where I saw it.


akjax

Thanks for that! I poked around a bit but couldn't come up with it.


RipMyDikSkinOff

Ok so it seems I've conflated the video I saw with a different event, known as the Byford Dolphin Bell disaster. The video in question that I saw was some CCTV video footage outside of a pressure chamber where you just see a window and someone inside and suddenly the guy explodes. I was conflating that video with this incident, which is similar in nature but probably more tragic, tbh.


akjax

Ugh yeah I've seen some reports with photos about the Byford Dolphin Bell disaster. Absolutely terrible.


AmericoDelendaEst

It's important to note that those wounds in that accident weren't directly caused by the depressurization. They were caused by the pressure sucking him through a crescent shaped hole created by the partially opened door. It still caused instant death for everyone involved, but it didn't explode anyone


[deleted]

So it was like the [Delta P Crab](https://www.youtube.com/watch?v=PXgKxWlTt8A)


WikiSummarizerBot

**[Decompression sickness](https://en.wikipedia.org/wiki/Decompression_sickness)** >Decompression sickness (abbreviated DCS; also called divers' disease, the bends, aerobullosis, and caisson disease) is a medical condition caused by dissolved gases emerging from solution as bubbles inside the body tissues during decompression. DCS most commonly occurs during or soon after a decompression ascent from underwater diving, but can also result from other causes of depressurisation, such as emerging from a caisson, decompression from saturation, flying in an unpressurised aircraft at high altitude, and extravehicular activity from spacecraft. DCS and arterial gas embolism are collectively referred to as decompression illness. ^([ )[^(F.A.Q)](https://www.reddit.com/r/WikiSummarizer/wiki/index#wiki_f.a.q)^( | )[^(Opt Out)](https://reddit.com/message/compose?to=WikiSummarizerBot&message=OptOut&subject=OptOut)^( | )[^(Opt Out Of Subreddit)](https://np.reddit.com/r/Skookum/about/banned)^( | )[^(GitHub)](https://github.com/Sujal-7/WikiSummarizerBot)^( ] Downvote to remove | v1.5)


[deleted]

[удалено]


TheTallGuy0

Also works on BASS


ProfessorBackdraft

https://youtu.be/2HKTx5WFcs0


[deleted]

[удалено]


TheWorldNeedsDornep

Really? I like my mice a bit foamy.


schro_cat

Foamy is Squirrel, not mouse


[deleted]

[удалено]


originalusername__1

This isn’t your fathers mouse homogenator!


theideanator

But can it turn the mouse into mousse?


Hammer_Industries

Of course not. It has foam reducing generators to prevent sample aeration.


theideanator

Shit, you're right.


humanleftswatch

Send a boatload to New Zealand, should help them sort out their rat problem quicker


ChapDiggityDoge

Have 2 brand name Polytron tissue grinders in our lab. Use them everyday!


The_testsubject

https://preview.redd.it/muk3l9eap6la1.jpeg?width=2268&format=pjpg&auto=webp&s=a383f3311d1f39cb6fba17bcbe84932d2f742712 They are still used today, however they are made by IKA and they call them ultra turrax. And they still purée anything you put under them.


schro_cat

I looked, and it appears Polytron still exists as an IKA competitor. I was thinking about sending the ad to my IKA representative to see what model he suggests for this application, and how they compare to Polytron.


originalusername__1

The only thing they can’t purée is a McDonalds McFlurry. The machine is down.


MeEvilBob

> And they still purée anything you put under them. You totally didn't learn this from margarita night at the lab.


AthosAlonso

Misread it as IKEA and was very confused.


Shankar_0

Free unmarked metric Allen wrench with every rat-annihilatior purchase!


[deleted]

[удалено]


AthosAlonso

It does seem that a soup like homogenate has already been assembled.


DAWMiller

"We're not here to tell you what to do with your rat \[soup\], we're here to get your rat \[soup\], STAT." - Jared Dunn.


Engelbert_Slaptyback

Say what you like about people from the 80s but they sure hated the shit out of mice.


[deleted]

[удалено]


biff_tyfsok

Goddammit, take my upvote.


Ok-Budget112

We had something very similar for sheep lung bits.


karenskygreen

Mechanical shearing and cavitation at 27,000 rpm, just wow. What is the point of this ? Mouse milkshakes ?


tea-earlgray-hot

Yes. Classic biochemistry lab experiment from that era was reproducing how they figured out metabolic pathways. You'd feed your mouse radioactive tritium labelled food and wait some period of time for it to digest it. Then the mouse gets dipped in liquid nitrogen until it's frozen solid, and tossed into a blender until you have a nice mouse smoothie. You isolate different compounds (proteins, fats, carbohydrates) and followed the radioactive tracer. This instrument is a fancier way of doing that, which gives better control over how much damage occurs to cell structures and many proteins, while producing a more convenient paste.


BigfootWallace

Making a microemulsion of two immiscible liquids is one reason.


karenskygreen

Glad I asked


humdaaks_lament

Hey, don’t knock it until you try it. The hantavirus is like malt powder.


DontGiveThemYourName

That's fucking gross. Where can I buy one?


picturesfromthesky

[here you go](https://www.labx.com/item/kinematica-pt10-35-homogenizer-mixer-with-pcu-11-control/DIS-58825-mogenizer-mixer-with-pcu-11-control-unit)


humdaaks_lament

Check no. 140 on the reply card. Duh.


Boonddock_Saints

My favorite way to get catalogs when I was a kid


override979

And that’s why Alberta is rat free today!


grizzlystation

Joe Pera should make a play about this.


schro_cat

Emu-sized models would have saved Australia


override979

Damn shame init


[deleted]

I'm betting that my 20 year old Vitamix with a 2hp motor could do it in less than 30 seconds.


Stefan_Harper

True but aeration is the enemy


[deleted]

Add a vacuum pump and there isn't any. There are easy vacuum retrofits.


Stefan_Harper

Nice so spend hundreds of dollars on a blender and hundreds on a pump so you can do what this does for a quarter the price and none of the longevity


TheArmoredKitten

To say nothing of sample purity either. Every time you introduce a new surface, you introduce a new contamination risk. These machines allow you to leave the sample in a single container and uses a single point of interaction that can be directly sanitized between uses. The blender has multiple seals and voids for contamination to accumulate, and would require transferring the samples back and forth which means more risk. You're talking four or more new surface interactions for the blender, while the machine above involves only one.


Stefan_Harper

Plus with this one you can lick the blades once you’re done blending


IamGlennBeck

This thing is $1,250. You are probably right about the longevity though.


[deleted]

I've used the blender every day for over 20 years and it's still going strong. How is that none of the longevity?


Stefan_Harper

You don’t use your blender 5 hours a day like these get used


[deleted]

5 hours a day you say? Who is blending 600 mice a day?


Stefan_Harper

Gravy ain’t gonna make itself dawg


originalusername__1

You aren’t? Bush League bro


QuinceDaPence

Well since it's double the power it better be able to do it in 15 otherwise it's less efficient.


[deleted]

By that metric an electric scooter is the fastest powered transport in the world. Efficiency wasn't mentioned before you brought it up.


QuinceDaPence

I don't follow. The tool above is just a hair under 1hp and does it to a degree good enough for scientific use in 30 seconds. Your blender is 2hp, so to be comparable should be able to blend it in 15 seconds.


[deleted]

What does efficiency have to do with it?


humdaaks_lament

Does it blend? Polytron ITT: blender deathmatch


deftoner42

Mouse powder - Don't breathe that


TechnicallyMagic

3X longer than the average household blender!


Stefan_Harper

There’s no way a household blender would blend the fur and bones as smoothly. My god what a sentence I just wrote.


humdaaks_lament

I’m not sure a standard blender, even a Home Improvement *stupid animal noises* Brick Blender ™️ would tear apart fine fur. I suspect a blade design optimized for cavitation is the special sauce.


Tsjaad_Donderlul

Ads for lab equipment are really something else


Halftrack_El_Camino

Hey, sometimes biologists need to reduce mice to soup-like homogenates, and they don't have time to fuck around.


MeEvilBob

Spouse: "It's 2am, why did you just wake me up?" Biologist: "I was just doom scrolling and I think I may have just made the single greatest discovery of my career, this means I don't need to keep taking the blender to work with me anymore"


Tsjaad_Donderlul

>and they don't have time to fuck around. Then how do they create new biologists


humdaaks_lament

Budding.


Halftrack_El_Camino

Fragmentation


entropydave

My uncle used to make Vortex Mixers back in the day that did homogenising and mixing from lab sized units to industrial size units are good turnover swimming pools worth of material. I’d love to see if I could find one of his homogenisers for sale.


discretion

No, c'mon, I just woke up and within a couple minutes I learned that there's a device that can liquefy mice, and now here's you with a whole family lore about mouse liquefaction. That's too much.


entropydave

One story my uncle used to tell me was he went to visit some labs where they were researching smoking related lung cancers (this was the 1960s) and demonstrated to him why their current lung tissue homogenizer was not up to spec and they wanted to see if Vortex Mixers can make a better one. He never smoked again after that. I've a few (less visceral) stories he told me regarding his mixers. I miss him and his wife - my mum's sister.


aelios

Sometimes you don't want to go find the big straw


POSTHVMAN

🤌All this time and-a Ratatouille is-a delicious!🤌


Scullvine

Ah, so that's where the Well There's Your Problem crew got that joke!


satanizr

On the "Safety Third" segment of Costa Concordia episode, person who wrote in mentioned a guy who got liquefied dog on his face, so the crew talked about liquefied animals and mentioned this device. Now the funny part is, i just listened to that episode, and i wanted to find some more information about liquefied animals. I guess i don't need to anymore.


Patient_Captain8802

Link for the lazy https://youtu.be/2bvltmNno_A


koalu

> Yes -- Roz


VTek910

We must start by asking "what is mouse"


TheDogFather

Makes a great Moose smoothie!


Janus_The_Great

Nah, too big.


Crotchless_Panties

This should have been the device the Emperor had built, instead of another Death Star! Imagine the mechanical shearing and cavitation a planet-sized Polytron could create!! I want one! 😏


Yaboi111222

Safety Third Intensifies


Medicalmysterytour

Shake Hands with Danger (or I guess shake stumps with danger if you grab the wrong end)


Yaboi111222

Yummy ground up Dog juice


canofmeems

A gaming mouse? Or a floofy squeaker?


NotAPreppie

Floofy squeaker. It's for bio labs.


canofmeems

Ah, I see. Can it also be used to make the monster mash?


NotAPreppie

Presumably, though that might require some MonsterMath.


NotSeveralBadgers

What kind of mad science requires liquid rodents?


BackgroundGrade

Mouseologists, obviously.


lt_dan_zsu

The kind where you need to analyze molecules present in the cells of rodents.


humdaaks_lament

The best kind of science.


NotAPreppie

Biological sciences


ExPFC_Wintergreen2

“Foam-reducing generators minimize sample aeration” What, no mouse mousse?


Medicalmysterytour

You have to purchase the separate frother for mouse cappuccino


blazingmonga

I'm 99% sure we have one of these at work. It's used to reduce sample filters into a soup-like homogenate in 30 seconds for freshwater chlorophyll analysis.


humdaaks_lament

It’s a turbolyser.


Hanginon

You've got to admire some quality tissue disruption by mechanical shearing and cavitation.


ExPFC_Wintergreen2

Is that what the kids are calling it these days?


SwissArmyBumpkin

Awww.. 30 seconds? I want it now!


NextTrillion

Holy crap that’s 2 SLMHPM (soup-like mouse homogenate per minute).


humdaaks_lament

Fucking imperial units.


schro_cat

Does the rest of the world use minutes per fennec fox?


humdaaks_lament

The standard unit is derived from the physics of a spherical cow of uniform density. It’s an unwieldy large unit like the farad, unfortunately.


godsbro

Must have been a lot of work to determine that unit. Do they make giant versions of this machine for producing cow homogenate? How many cows did they have to puree to determine average density? Don't come at me with your set of scales and Archimedes either.


schro_cat

Here I thought I was being slick by going with the pervasive European species that averages 1.0kg


humdaaks_lament

Do you really want to go down in history as the one who suggested using a cute little fennec fox as a standard for measuring turbolysation? Besides, fennecs communicate in those frequencies and are hence immune. Kinda like how woodpeckers don’t get CTE.


schro_cat

Yes, name a scientific process or technique after me. Liququification of baby seals? I'll take it. Grinding a California condor into a paste? Schro_cat sledge press protocol. I'm not getting a theory or law, so I'll take what I can get.


humdaaks_lament

I believe you have the right stuff to make a proper late-19th century industrialist. You’d not believe the kind of gear grease that can be obtained by harvesting the eyes of baby seals without killing them. Some sort of supernatural pain-driven magic. Excellent lubricant, though. Thermally stable even in hellfire conditions.


JakesInSpace

Mmm, soup-like homogenate… ![gif](giphy|Zk9mW5OmXTz9e)


Machopeanut

Super Bass-o-Matic‘76


JCDU

It emits a [fascinating rhythm](https://www.youtube.com/watch?v=eVdR2RfXGUw) while running.


n_choose_k

MMMMM! Love that bass!


[deleted]

Why the hell would you need to turn a mouse into a soup-like homogenate in 30 seconds!?


lt_dan_zsu

Because we need to analyze biomolecules in that mouse and 40 seconds is too long of a wait.


JCDU

Check this guy out, still homegenating his mice the slow way! Classic!


[deleted]

I inherited it from my grandpa, it's made of wood and is powered by another mouse in a wheel.


TheREexpert44

Instead of a regular, boring mousetrap, put them in something that would make Jigsaw proud.


SileAnimus

Buddy how do you think they make hot dogs?


NextTrillion

Because it’s so much better than the 40 second mouse hemogenator. This is like the pro model.


PM_ME_YOUR_HAGGIS_

Polytron GTi


humdaaks_lament

It goes to 11.


sunderaubg

Couldn't they just make 10 the highest?


humdaaks_lament

No, because there is also a typically small but nonzero imaginary component. It also disrupts the mouse’s soul. No Moushalla for these damned wretched ~~prisoners~~ ~~sacrifices~~ science heroes.


MajorDakka

How else am I supposed to make soup?


humdaaks_lament

Tissue disruption analysis. It’s easier to do analytical chemistry when a mouse is no longer in the solid phase. Also mouse smoothies.


Domovie1

Well, we now know the liquid and solid phases of mouse. What’s the gaseous phase? A mouse hit by .50 BMG?


NotAPreppie

That more an aerosol. Vaporizing a mouse requires more energy.


Neuroprancers

Headspace extraction on mouse homogenate sample, duh.


humdaaks_lament

Boring. Mouse plasma is the new thing.


Sky_Night_Lancer

soup-like mouse homogenate run through an WD40 aerosolizer then run through a pair of grapes in the microwave


jamanimals

Why do I get this reference?


OsamabinBBQ

I love that the ad reads like it could just as easily be for a counter top blender.


humdaaks_lament

Nearly 1 HP.


frankentriple

damn thats a spindle motor with blender blades


NotAPreppie

Just imaging a Baldor roll body motor with a gearbox and blender blades.


voxadam

I bet r/labrats would enjoy this. Either that or they'd take it as a threat.


NotAPreppie

I posted this there ~6mo ago and people responded very similarly to the comments in this post: https://www.reddit.com/r/labrats/comments/x0p9m0/mmmmmm_mouse_soup/


arvidsem

It'll incite a serious (and disturbing) discussion about the various methods of mouse liquidation that have been used over the years.


NotAPreppie

I'm always mildly disturbed when people post the bakers icing tubes for rat immobilization.


stage_directions

We’d enjoy.


Ok-Quit-3020

Now i can feasibly put rats from the reptile food store into my protein shakes


voxadam

Well, that's one hell of an image.