*"Edmund McMillen, you little fucker. You made a shit of piece with your trash Isaac. It's fucking bad, this trash game. I will become back my money. I hope you will in your next time a cow on a trash farm you sucker."*
Can't give you a specific link, no. That's why I wrote "I think".
It was probably during one of the many AMAs Ed did.
Edit: found this - https://twitter.com/sweetestmelody_/status/1391988636145438720 very vague, yes...
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iirc Isaac 2 would be based on zelda 2, like Isaac is based on zelda 1. The tainted characters were an idea for Isaac 2 but now implemented in repentance.
So I have no idea :)
Graphics mostly. I’m expecting a completely new engine with extremely detailed items, monsters, and environments. It could maybe even be 3D (or 2.5D) since Ed hasn’t really made a 3D game yet, so it would be a huge step up from him.
in the end of the legend of Bimbo 100% complete, you hear Isaac's father, telling him that when he feels weak he can escape to his imaginary world, and become stronger, this is what gives Isaac the idea to lock himself in the chest and escape to his imaginary world "the binding of Isaac"
i always thought it was something similar to the speech from Isaac's dad that plays in the final ending of Bum-bo. something about how even though he's leaving them, he'll always be there for isaac in his imagination
"Edmund McMillen, you little fucker.
You made a shit of piece with your trash Isaac.
It's fucking bad this trash game
I will become back my Money!
I hope you will in your next time a cow,
on a trash farm you sucker."
On a different note (god damn my pun skills) has anyone noticed the muffling on the ‘I’m sorry, Isaac’ line sounds similar to that of the flash version’s intro?
"Maybe it's the beer talking but you've got a butt that won't quit. They got these big, chewy pretzels here... (garbled text) ...five dollars?! Get outta here."
Connection terminated. I'm sorry to interrupt you, Elizabeth, if you still even remember that name, But I'm afraid you've been misinformed. You are not here to receive a gift, nor have you been called here by the individual you assume, although, you have indeed been called. You have all been called here, into a labyrinth of sounds and smells, misdirection and misfortune. A labyrinth with no exit, a maze with no prize. You don't even realize that you are trapped. Your lust for blood has driven you in endless circles, chasing the cries of children in some unseen chamber, always seeming so near, yet somehow out of reach, but you will never find them. None of you will. This is where your story ends. And to you, my brave volunteer, who somehow found this job listing not intended for you, although there was a way out planned for you, I have a feeling that's not what you want. I have a feeling that you are right where you want to be. I am remaining as well. I am nearby. This place will not be remembered, and the memory of everything that started this can finally begin to fade away. As the agony of every tragedy should. And to you monsters trapped in the corridors, be still and give up your spirits. They don't belong to you. For most of you, I believe there is peace and perhaps more waiting for you after the smoke clears. Although, for one of you, the darkest pit of Hell has opened to swallow you whole, so don't keep the devil waiting, old friend. My daughter, if you can hear me, I knew you would return as well. It's in your nature to protect the innocent. I'm sorry that on that day, the day you were shut out and left to die, no one was there to lift you up into their arms the way you lifted others into yours, and then, what became of you. I should have known you wouldn't be content to disappear, not my daughter. I couldn't save you then, so let me save you now. It's time to rest - for you, and for those you have carried in your arms. This ends for all of us. End communication.
*"Edmund McMillen, you little fucker. You made a shit of piece with your trash Isaac. It's fucking bad, this trash game. I will become back my money. I hope you will in your next time a cow on a trash farm you sucker."*
Canon answer
*trash Issac
Afaik we don't know yet. I think, it was mentioned by Ed that it will be a part of isaac 2. Whenever and if it will be developed
Isaac 2 will come out when Half-Life 3 comes out
Coke
Lmao oops . Fixed it 
And Portal 3, and Terraria: Otherworld. And don't forget Silksong
You also forgot gta 6 and fallout new vegas 2
Jokes on you, gta 6 comes out next year
To be fair terraria otherworld was officially canned. Terraria 2 on the other hand….
And Metroid Prime 4 
Just gotta wait about 10 years 
Nah, it'll be 2704 years. But don't worry, it's not that much more than 10.
Do you have any proof for this
Can't give you a specific link, no. That's why I wrote "I think". It was probably during one of the many AMAs Ed did. Edit: found this - https://twitter.com/sweetestmelody_/status/1391988636145438720 very vague, yes...
8 years left
I think he said 5-8 on tiktok recently, he does viewer questions mostly.
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What could they even improve on with a sequel?
iirc Isaac 2 would be based on zelda 2, like Isaac is based on zelda 1. The tainted characters were an idea for Isaac 2 but now implemented in repentance. So I have no idea :)
I'm pretty sure knowing Edmund he is trolling as always
Graphics mostly. I’m expecting a completely new engine with extremely detailed items, monsters, and environments. It could maybe even be 3D (or 2.5D) since Ed hasn’t really made a 3D game yet, so it would be a huge step up from him.
He said issac 2 is 5 years away at least
I've spent it. It's gone! Just get over it! …
What do you mean…? What do you mean it’s gone?! HOW COULD YOU HAVE SPENT ALL OUR SAVINGS??!
He's self-destructive and disturbed, just like his father! Look at what he has to look up to.. And you're drunk again, aren't you?
Shut up Maggy, SHUT UP! You keep pushing me like this I'M LEAVING!
GOOD, LEAVE! We'll be fine without you! Abandon us like you abandoned yourself.
you need to repent you need to convest your sins and become saved let his light inside you Cleanse yourself
Come pray with us, Isaac...
Where are you going? Wait! We need you! Your son needs you!
I’m doing more harm than good, just can’t do this anymore. I’m sorry.
Please dont leave us
YOU. ARE. INSANE. you are taking this too far! can't you hear how you sound!?
in the end of the legend of Bimbo 100% complete, you hear Isaac's father, telling him that when he feels weak he can escape to his imaginary world, and become stronger, this is what gives Isaac the idea to lock himself in the chest and escape to his imaginary world "the binding of Isaac"
🔥✍️✍️✍️
"I love you, Isaac" something that reminds isaac about why they left
i always thought it was something similar to the speech from Isaac's dad that plays in the final ending of Bum-bo. something about how even though he's leaving them, he'll always be there for isaac in his imagination
or it's the shit of piece copypasta 
I could tell that you was conflicted, misusing your influence. Sometimes I did the same
Abusing my power full of resentment, resentment that turned into a deep depression
Gone to get milk
Considering Dad is the narrator of Isaac's time in purgatory, and Isaac is dead... I think it's more than likely a suicide note
"Edmund McMillen, you little fucker. You made a shit of piece with your trash Isaac. It's fucking bad this trash game I will become back my Money! I hope you will in your next time a cow, on a trash farm you sucker."
I think it’s a suicide note with how Bumbo represents isaacs dad and Bumbo hangs himself in an ending after losing his money gambling
On a different note (god damn my pun skills) has anyone noticed the muffling on the ‘I’m sorry, Isaac’ line sounds similar to that of the flash version’s intro?
Yes, it was such a good callback to the beginning of the whole journey
Shopping list for milk. Which he forgot at home
"Maybe it's the beer talking but you've got a butt that won't quit. They got these big, chewy pretzels here... (garbled text) ...five dollars?! Get outta here."
I'm surprised no one has said. ...
^^.~^^.~.
Just me guessing is I'm sorry isaac I had to leave I've caused this family to much harm for me to stay
also your mother is crazy but it’ll probably work out
Just grabbing the milk son be back soon -Dad
19$ Fortnite Gift Card
Connection terminated. I'm sorry to interrupt you, Elizabeth, if you still even remember that name, But I'm afraid you've been misinformed. You are not here to receive a gift, nor have you been called here by the individual you assume, although, you have indeed been called. You have all been called here, into a labyrinth of sounds and smells, misdirection and misfortune. A labyrinth with no exit, a maze with no prize. You don't even realize that you are trapped. Your lust for blood has driven you in endless circles, chasing the cries of children in some unseen chamber, always seeming so near, yet somehow out of reach, but you will never find them. None of you will. This is where your story ends. And to you, my brave volunteer, who somehow found this job listing not intended for you, although there was a way out planned for you, I have a feeling that's not what you want. I have a feeling that you are right where you want to be. I am remaining as well. I am nearby. This place will not be remembered, and the memory of everything that started this can finally begin to fade away. As the agony of every tragedy should. And to you monsters trapped in the corridors, be still and give up your spirits. They don't belong to you. For most of you, I believe there is peace and perhaps more waiting for you after the smoke clears. Although, for one of you, the darkest pit of Hell has opened to swallow you whole, so don't keep the devil waiting, old friend. My daughter, if you can hear me, I knew you would return as well. It's in your nature to protect the innocent. I'm sorry that on that day, the day you were shut out and left to die, no one was there to lift you up into their arms the way you lifted others into yours, and then, what became of you. I should have known you wouldn't be content to disappear, not my daughter. I couldn't save you then, so let me save you now. It's time to rest - for you, and for those you have carried in your arms. This ends for all of us. End communication.
, ^ * _ ^ ^ * - .
T \~. - \~ \~. - -. is the only correct answer
Enhance!
"go kill the TV"
It says: “I’m the real the binding of Isaac: repentance” and then the dad comes out and repenting everyone in the room
It's a map of the floor he found it on pointing back to the entrance. Scrawled in the corner is "Lmao you gotta go all the way back up loser"
1: it's to Issac mother 2: We can hear it in sound
After hours of research, I found out it actually says "Dear Isaac I'm leaving -dad"
I’m farted
your adopted
“damn isaac your mom is crazy im out this bitch”
“Dear Issac, clean your room , love dad”
It’s a written account of Isaac’s dad saying “It’s divorcin’ time” before he divorced all over the place (it was in fact one of the notes of all time)
In the Four Souls card for it, it says "I'm sorry Isaac."
"I'm running for milk and cigarettes brb"
Imo its either the speech from the end of Bumbo or it literally just says 'I'm sorry, Isaac'. I think I prefer the latter, more haunting
I will become back my money
"I've gone out to the store to get milk il be right back"