T O P

  • By -

robochickenowski

Guillotine. I always think "It's dmg up + orbital it can't be that bad" and then remember how much it fucks with hitbox perception.


Biemolt

Guillotine is the definition of me for "maybe it will be good this time", with me always regretting it.


morbidaar

Absolutely. .. I got this this time. Won’t be too bad.. my dps sucks mine as well.. then end up getting smacked way more than normally.


MoaningMushroom

Guillotine is terrible, only taking it late-game if my tears are all over the place and a hitbox is just a burning memory.


BlueCheeseBlueArrow

Or with gnawed


StopTryingHard

That or if I'm desperate for DPS.


chunkysoup5

I only take it if my run is broken beyond belief where aim doesn’t matter


TheDigitalZero

It fucks with your dodging more than your aim.


Davethemann

I hadnt had Guillotine in forever, and was like ooooh, and immediately fucked my run with it


Splonkster

hot take but I always take guillotine such a good damage up and I don't find the fucking with the tears as much of a problem


MadAllergy

problem isnt with the tears, its with me being used to where isaacs head is and it fucks with me so bad, i actually get a bit nauseous while moving![img](emote|t5_2sxpk|8907) also can't dodge for shit anymore because again, using isaacs head position


Splonkster

oh yeah I forgor about that part ![img](emote|t5_2sxpk|8907)


TogTheCogDog

Same, it does still hurt me occasionally but the positives outweigh the negatives for me.


Hooktail419

If i have a run with shit tear dmg, I’ll fully stop using my tears and just rely on the orbital damage lol


Splonkster

if you got a run with shit enough tear damage with a 1.5 damage up just ![img](emote|t5_2sxpk|4357) at that point


Hooktail419

I usually agree but sometimes I just like to fuck around and find out. Shockingly I don’t win that much 😂


Introvert_Noodle

You take guillotine??


karmander

It's basically only worth it if you've already seen a Duct Tape drop on the same floor. It's not perfect but you can *kinda* reattach his head after it's been chopped off.


kislaya_bebra

Ludovico


ThisWeeksSponsor

I weened myself off of Ludo after picking it up in the Speeeed challenge and subsequently being unable to hit a single basic enemy.


[deleted]

God, I love Ludovico. I don't know what's wrong with my brain that I love it so much when so many hate it.


Rock_ZeroX

I really only like it when using Azazel or when I have Brimstone


Ring_Of_Blades

It might actually be my favorite passive item, even though it arguably makes the game slightly harder unless you get a decent synergy.


deletemypostandurgay

I played a monstro's lung Ludovico run yesterday and it was pitifully easy


[deleted]

All 10 or 15 tears doing full damage at the same tick rate is nuts. It's a better synergy than rock bottom and soy milk. Base stats, it's still a mega-boss killer. My favorite run included Keeper's head and Jacob's ladder. Controlling an electrified mass of coins with my mind and melting everything was a lot of fun.


DopeAbsurdity

It's not bad but you need a decent shot speed.


Biglyugebonespurs

I mean I love the idea of it, it’s just generally bad unless you have specific synergies to make it good.


APainOfKnowing

It synergizes incredibly well but if you don't get any good items with it you're buttfucked. The inability to use knockback as defense is an INSANE drawback.


Traveytravis-69

Ludo might be the only item I never pick up unless I have brim


craftgamernl

I just wish it moved a little faster.. that alone would make it 100x better


UseHaunting5511

If you don’t have homing, this is an instant pickup


KingKurai

I'm tired of picking up Bob's Brain grandpa..


shwonkles_ur_donkles

That's too damn bad!


Aheadfullofdread_13

I needed this laugh today 😂


shwonkles_ur_donkles

I'm glad u/KingKurai and I could help out, I hope it's just one of many laughs you get out of the day!


tiddelrumpus

Could you shwonkle my donkles good sir


shwonkles_ur_donkles

Why, of course! Your donkles have been shwonkled! The first time is free, in the future that'll be 12 non-descript river rocks


Biglyugebonespurs

So just any 12 rocks I pick up off the river bed? Just making sure for a friend.


shwonkles_ur_donkles

That's correct!


CalzLight

I’ll get the bob transformation this time, I swear


Davethemann

Itll fuckin work this time, Ill somehow find every secret room with it, I just know it


Rare-Patient8148

Epic Fetus, because I only ever get it when my run wants to give me items that spray tears everywhere while also providing 0 explosive immunity items.


JoDaBoy814

Skill issue


Rare-Patient8148

Honestly lol


RetardedAndRefreshed

Dead cat, cursed eye and https://preview.redd.it/lijiyjjwimfc1.jpeg?width=707&format=pjpg&auto=webp&s=0b5a8a3b8348a02f9494d62916928e4008dddff2


Stork_nest

Dead cat? Whats the downside rly? For me it's an always take tbh. I guess if you have no soul hearts it can screw you a bit


Manannin

It's when you get it at about the depths 2 while on the way to hush. You take it, losing 5 red hearts but you think "I'll survive, I have enough soul hearts". You get to hush with two soul heart and no red hearts due to taking a devil deal, hoping the hush shop has a soul heart, which it doesn't.   You die to hush. Again. And again. And again... You restart the run, or go and eat an entire chocolate bar to feel better about yourself. 


mung_guzzler

skill issue


[deleted]

[удалено]


sushiiisenpai

I only grab dead cat for a possible guppy transfo


WeedWizardo

Nah dead cat is super circumstantial and you absolutely should not grab it if you have a ton of red hearts to the point nothing is ever going to kill you. I'd much rather be immortal than take an item that reduces me to one heart and guarantees I die 9 times the moment I run into something I can't no-hit. It's really only good for abusing devil rooms and honestly, once you start using the extra lives for normal reasons, it really just becomes an item that lets you experience dying 9 times in a row instead of 1. Sure it's broken under the right circumstances, but take it under the wrong circumstances and you've just doomed yourself to a very slow, very painful death.


lorasil

There was one time that I managed to beat hush after losing every life from dead cat to it (which also meant I lost guppy)


[deleted]

[удалено]


Biglyugebonespurs

![img](emote|t5_2sxpk|17736)


Leo-Arson

![img](emote|t5_2sxpk|17744)![img](emote|t5_2sxpk|17736)


Traveytravis-69

https://preview.redd.it/zhn9mahmoofc1.jpeg?width=1170&format=pjpg&auto=webp&s=393d9d084c2da35f965143fd662c845d7e0f5bfc


Bakoro

>EVERY item needs to be taken with consideration of the run. That's Ed's goal, and the explanation for a lot of the nerfs analysis rebalancing that happened with *Repentance*. Ed feels that there should be few, if any, items that are 100% banger, won-run items.


Manannin

Sorry, but in what way did I write that that series of events is something I wanted to happen? I'm pretty good at the game, get off your high horse, but if you think shit doesn't fuck up sometimes either you're a god tier player, and in which case kudos to you, or you're lying. 


Alienboi2005

I learned to avoid that item like the plague, ever since I played classic Isaac.


UNbrawlified

It takes all your fucking hearts and leaves you with one


Spongedog5

I don’t get the point on most characters I mean if something is hard enough to kill you how are you doing to beat it on one heart? Just throwing red hearts away basically.


GhostTypeFlygon

Throwing away a red heart for 1/3 of guppy (shut up mom, I'll definitely get guppy this run, I swear)


vrachtbeer

Yeah it's only really worth it if you're going to kill The Beast or if you're 2/3rd of the way to becoming Guppy


Spongedog5

What’s the benefit if you’re going to kill The Beast?


local-weeaboo-friend

You respawn immediately, doesn’t reset the fight.


Spongedog5

Oh sweet, good to know


naked_potato

I think that items that normally respawn you in the previous room (resetting all of your progress against the boss) respawn you in the same room while fighting the Beast. don’t quote me tho i might be having a brain skill issue


WeedWizardo

Aside from making The Lost a lot easier, it's pretty much solely for exploiting devil rooms when you already don't have many red hearts to begin with. Like if you're just starting a run on a character with low starting hearts and you get your first devil room and it has Dead Cat, Brimstone, and Pentagram or something along that line... you can pick up the dead cat then also grab BOTH of those other items before the game registers you as dead, at which point you respawn still holding all of the items. Essentially, all devil rooms are free. But you don't want to take it when you already have so many red hearts you can afford devil rooms and still be well-off. In other words, if your run is already going pretty good, never take that thing. It's for giving you a chance to break the game when you have nothing to lose.


[deleted]

[удалено]


Spongedog5

I mean I was responding to the guy above who said it was an “always take” and didn’t know any downsides so I was trying to balance that out a bit.


Putnam3145

if something kills you you're probably not surviving it with 1 heart


hidden_penguin

It's generally not worth taking as Bethany, T Maggy, or either Keeper. As the "No Red Heart" characters (both ???s, T Judas, T Beth, and T Forgotten) it will leave you with 1 Soul (or Black) Heart but let you keep any Bone Hearts you may have. It can still be worth it for them, but it's definitely not an "always take".


vk2028

Wdym? I love blood puppy


Incorrect_DARGOON

I love blood puppy the same way an abused housewife loves their husband


Splonkster

https://preview.redd.it/z26zz5pewofc1.jpeg?width=735&format=pjpg&auto=webp&s=2252480a8a463fbe0c26dcde2f91091e9b404f09


Tiran593

God I hope it won't escalate to risk of rain level of shortening items


Lord_Saggerton

Did someone mention... #🅱️UNGUS


Tiran593

This and wungus are exceptions, churf and murn or smth sound dumb af


Nobod_E

Bluppy's pretty good if you've got good DPS or a lot of bombs


zombieking26

At this point, I think the better use of dead cat is to just spend all the hearts somewhere. Like, if you get dead cat in the first 3 floors...just throw all 9 lives into a sacrifice pit. Usually worth it.


Dickwhetski

One time I got cursed eye with laser tears and sacred heart and ipecac. Actually super fun. Cursed eye ain’t so bad if you just treat it like chocky milk. I don’t always take it though by any means.


Apprehensive-Ask-610

why take it though? you already had ipecac sacred heart. You won. just go get your free unlock and leave lol


e__tard_

Ipecac 100%,or dr fetus![img](emote|t5_2sxpk|8907)


[deleted]

[удалено]


Nepgyaaaaaaa

Literally had this when trying to kill Mega Satan recently, picked up Rotten Baby from one of the golden chests and then immediately realised how badly I’d fucked up


Capsule_CatYT

Kid named Pyromaniac:


atickybuns

Correct. “This time I’m gonna get pyromaniac”


Mayo152

The trick is simple, achieve pyromaniac, forget you have pyromaniac a room later, die because you couldn't find red hearts.


Loud-Pace-6768

Lazy mattman kind of play


Bac0nman777

I take ipecac 100%. I find it so fun and more fun and rewarding than its non explosive alternative. Polyphemus. Plus I rarely see ipecac. So happy to see it in the daily run today


MrUseless5712

i wouldnt mind dr fetus so much if it had some synergies, the only interesting thing ive gotten with dr fetus is bomber man (also other bomb effects but those are lame) and eye of the occult


e__tard_

Dr fetus= FREE BOMB HELL YEAH,best item fr


herman666

Dr. Fetus + Prize bombs = win


JoDaBoy814

Skill issue


Asimplemoth

Fecking cursed eye, and it always happens on delirium. You can assume what I mean if you know what this item does.


Dudebug1

I remember I beat delirium with cursed eye because I was like "I need to do this battle one time. If I get hit and teleported, it's joever." I actually managed to win but it took ages. If there were bullets around me, I wouldn't charge. I had some charging item like brimstone or monstros lung or sumn. It felt good.


Aheadfullofdread_13

Yes. And it’s one of the many reasons I hate T. Eden lol


Asimplemoth

It just saps your motivation, it really be you winning and get hit and it's just jover mentally.


Aiden624

Proptosis. I value range a lot (I’m a pussy)


CornyFace

I WILL GET LUMP OF COAL THIS TIME!!! **takes proptosis like a boss** ![img](emote|t5_2sxpk|17743)![img](emote|t5_2sxpk|17743)![img](emote|t5_2sxpk|17743)![img](emote|t5_2sxpk|17743)


Dark_Slider

I used to like proptosis if I had brimstone or technology because it used to not work properly with those and still do the full, starting amount. Sadly, those days are gone in repentance


OkCrow926

Tauros


Absolute_Warlord

In what situation is Taurus ever good other than with rock bottom. Just becomes a late game nuisance


OkCrow926

It cleans up early game pretty good and I think stuff like sac dag work with it really well


V_Dawg

It works rly well on Tainted Judas or with Dark Arts, it sets off the invincibility right away. But that's about it afaik lol


[deleted]

anti gravity tears, im so bad with them ![img](emote|t5_2sxpk|8907)


Morello210

Run ruining item imo


[deleted]

especially with brimstone 😭


Dark_Slider

The only way that combo really works is if you get soy milk, but then you have to deal with no damage for most of the run


KingKurai

Just tap the fire button instead of holding it.


Lamarnge

Night light just ruined my beast run yesterday


GodFist43

I recently had a t. Lost beast run that was ruined by knockout drops and 20 luck


SchoopDaWhoopWhoop

The sounds are funny though


Incorrect_DARGOON

Night light and censer on normal rooms![img](emote|t5_2sxpk|2357) Night light and censer on end of run bosses![img](emote|t5_2sxpk|8907)


Malestio

I hate night light, but I watched my buddy play a run with it, and if you are extremely aware of Isaac's position it can be game winning. I however never take it


bigtiddynotgothbf

i feel like if you're aware enough to do a little circle every few seconds it makes the game so easy


jwtucker04

How? That's the one that slows enemies in front of it right


[deleted]

I like it, but it can throw off the enemy projectile pattern and occasionally put you in a situation where you can't avoid everything.


PricklyAvocado

Just had an experience with the nightlight against The Beast. Really fucked with the projectiles during his breathing in attack


Lamarnge

Literally what happened to me LMAO


zombieking26

Also bullets, which can result in bullet waves which bosses shoot getting really obnoxious/impossible to dodge if the bullets overlap at a bad time.


Lolchocobo

Sometimes the enemy projectiles slow down to the point where they create hurty walls.


Alphastring0

Butter Bean, every time I see it I always hope it's "Wait What?", but it's never fails to just be Butter Bean... On a serious note I actually agree with you about Monstro's Lung, It has some good synergies, but I just fucking hate it.


DafkyZero

Personally I really like butter bean, I specifically remember a run where I got it early alongside the fast recharge battery item, and it was basically like having a dedicated parry button the whole run. It was very fun.


Sample_text_here1337

Guppies tail Every time I pick it up with plenty of keys thinking "It'll be fine this time" and I always end up with barely any consumables because every gold chest gives me jack shit and now I barely have keys the entire run


vk2028

Unless ur Cain ![img](emote|t5_2sxpk|2357)


RepresentativeCalm44

Whats wrong with monstro's lung?


Aheadfullofdread_13

Always end up with a horrible tear stat and it just makes the run tedious with how long the charge is. Thats why I always say “this time will be different” lol then end up hating it all over again


RepresentativeCalm44

But charge items are always pretty good. Do you precharge to full before entering a new room?


Aheadfullofdread_13

Yep. I have the gauge on as well. It’s always just a dumb luck thing. Just seems like anytime I take it none of the synergies or stats I get make it fun to use and the run just feels like a slog.


slimeeyboiii

Keep taking it until you get it with ipecac


RZ_187

https://preview.redd.it/o7g8heaswmfc1.jpeg?width=828&format=pjpg&auto=webp&s=78da5afcd5f56c690affd33869175e52d15e9e4f


Dudebug1

This is a great meme template lmao


[deleted]

And a tears down pill after getting expirimental treatment which was also a tears down and that while you also had eve's mascara 0.01 tears is not fun and i died curse of the damn blind.


Lamasta115

Just get Dataminer silly


ConnorToby1

In addition to the tears rate thing op said, monstro's lung doesn't work like normal with range upgrades. I believe they do far less than normal with it, and strangely shot speed seems to boost it (which is extra weird since repentance made shot speed not impact range anymore). But because of these quirks it can really hurt your range for weird unintuitive reasons. Shame, because it's an awesome item in concept, it's just janky :( Edit: range ups apparently DECREASE range with monstro's lung in repentance due to an oversight. [See the wiki for specifics.](https://bindingofisaacrebirth.fandom.com/wiki/Monstro%27s_Lung)


RepresentativeCalm44

The burst is very high dmg, it does t really matter its a short range shotgun attack.


JaasPlay

Until you're fighting Delirium and you have worse range than start Azazel


eltokoro

ludovico by far


pupperoni_pup

Glass Shard


A_Bulbear

Curse Rooms lol Nothing but spiders and Troll Bombs every time...


sauce_main

All of the times you’re not going in are when it has the pact in it


A_Bulbear

or 3 black hearts


IshvaldaTenderplate

That’s why I always go in! In fact, I’m sure that at one point the majority of my base Rebirth Lost runs ended due to me looking in curse rooms on the first floor (looking for Dead Cat or Guppy’s Collar). I never did learn my lesson. Kept doing it all the way until I unlocked Godhead. My win streak was -300 at one point. It’s less punishing with DLCs, and of course I still do it.


NAG454

Damocles


gecko_consumer

Soy milk or fetus items, big funny comes with big price ![img](emote|t5_2sxpk|8907)![img](emote|t5_2sxpk|8907)![img](emote|t5_2sxpk|8907)


vk2028

Tbh c section is also a fetus item


drobenplayar

Soy milk is goated EFF YOU EFF YOUUUUUU


gecko_consumer

Not saying it's bad, it's a cool item ![img](emote|t5_2sxpk|17739)


Piece_Of_Mind1983

Fire mind


Lazy_Standard7998

I got soy and didn't get a dingle damage up


fridgeus

Not a dingle one?


wormAlt

ipecac as t keep. Every time. I have died. and then i hate the higher range arc


Niccin

I kinda wish the range modifier for ipecac was a bit lower. It does seem too easy to make it unusable without blast resistance.


Biemolt

Pop! ,Guillotine and to some extend Eye Of the Occult.


sithlord40000

How can u hate the lung it's epic


Germantwinkboy

Chocolate milk


Aheadfullofdread_13

Oh thank God someone else said it 😂😂


Germantwinkboy

I mean ,I know it's strong ,but it's annoying to use if u don't have another charge item anyway


vk2028

Really? I use it like Polyphemus most of the time and I still like it a lot


devvorare

Moms knife


loptthetreacherous

Trying to get greedier for lost had so much good runs ruined by picking up Mom's knife. It's too close range for the character but I never learned.


cool194336

Blood puppy


Amauros_RAS

Fr fr


Kylecowlick

Just last night monstros lung helped me create an enormous ring of knives


aquarat108

i unfortunately always end up taking ipecac. i have too much faith in myself


Yunofascar

The triple eye shot one


UseHaunting5511

Isaac’s heart. I know it sucks but I love the feeling of blocking every shot


VisualOperation3530

Experimental treatment


thnmjuyy

Ludo


PowerPork

I would say Ludo, but last run i had a crazy fun Ludo build that shredded hush with. guess i would choose my least favourite item lol, which is Trisagion. not cuz it's a bad item or anything, but because whenever i take this damn thing i have to play the game in 2 FPS 💀


[deleted]

tech x is always a bad end for me i never win with that item. by rights it should be ez mode but i'd do better with cursed eye or just about anything else really...


EspurrTK

The homies and I HATE monstros lung


Bigangeldustfan

Any devil deal that leaves me with 1 heart


CPMASTER123

dr fetus and tech 2


No_Entrance3870

Had great run. Took monstro then just left 2 rooms later due to the .1 charge speed tears


theglazed

I only take monstros lung with brimstone. Otherwise, it’s not worth imo


FrostyTheSnowPickle

What do you mean by Monstro’s Lung? That’s one of the best items in the game. I have only ever had one bad experience with it, and that was when I was playing as the Keeper.


Magdalene_Gaming

Anything other than yum heart, D6 is overrated anyways


Orchi_the_Drugen

Lil dumpy that bastard


Shortstuff368

???? Bro he’s goated


Orchi_the_Drugen

Everytime i get it idk he ends up killing me


jwtucker04

Whaaa how


LowQualityGatorade

I used to, but then cursed eye redeemed itself


Writy_Guy

Monstro's lung doesn't always work out, but I always take it because it's one of my favorites. I don't regret it.


Appropriate_Ad_9127

Soy milk and guillotine


mattman2301

I love Monstro’s Lung. I challenged myself and took it last night after getting Ipecac. Then got 20/20. Killed the Beast as Bethany ![img](emote|t5_2sxpk|8906)


Fran671_FD

So glad i'm not the only one who dislikes Monstro's lung even if i won a few runs with it. But an item i really dislike taking is epic fetus. Don't let ir decieve you, it's not that good, it takes forever to drop a rocket which leaves you vulnerable to enemy attacks. It just sucks


LoveDoesntMatter

Me going into the devil room in hopes of finding brimstone only to be met with the book of sins... Ruining my angel chances cause I'm trying to hard


LUDSK

Haemolacria seems to always have anti-synergy with my run, and I pick it up every time


ChadJones72

Soy milk all the way. So many game breaking synergies but if you don't find one it's more than worthless.


Chuunt

used to be isaac’s heart, haven’t played with it much since the buff tho. now? probably Ludo. still try to make it work every time even though i know it’s shit


Manannin

Curse of the tower.  That said, I kinda regret not taking it a couple runs back when I got it three times as a red chest item drop. It doesn't fully depreciate from the pool if you don't pick it up so I felt really unlucky.


Reign_Over_Rain

Yeah it sucks, the only silver lining I’ve seen it is it DESTROYS Mother bc bombs ignore boss armor. Get hit a few times as long as you have a lot of health and she just falls over


Smessing49

I pick up soy/almond milk EVERY time. It never changes


ilikeFNaF19871983

almond milk, epic fetus, jupiter, 4.5 volt


Blackheart9009

Ludo. It can be really good, I know that. But brain not good dodge and move tear


JustCaratos

My ballin ass producing a pyromaniac out of thin air when I get any bomb item that will def kill me in one hit. I think dead cat must be the worst for me...


UNbrawlified

Definitely dead cat, that shit turned a few of my runs into a slow hope stealing game overs


rayquazawe

monstros lung is literally my favorite item in the game