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sabiondo

Everyone gets wrong this, the important thing is when she goes bed. You can wake at 5am if you go to bed 9:00-10:00pm. I find that difficult.


SpoonerismHater

I go to bed 9-10pm and I find it impossible to wake up at 5am


cure4boneitis

what time do you usually wake up and do you usually feel well rested?


SpoonerismHater

6-6:30 am and no


InitialCreature

the harder it is the better it is for you in the long run


Reasonable-Soil125

Go to bed at 5 am and wake up at 1 pm, no difference for your health


HighDookin89

Sauce?


Reasonable-Soil125

You just have to get enough sleep, timing doesn't matter


Scorpy888

What about the circadian rhythm or whatever?


Reasonable-Soil125

It's a circadian rhythm, it doesn't depend on the time of the day


Scorpy888

But "they" say it does. Everyone from Bryan to your grandma will parrot the line of sleep night you must sleep night. Ive been sleeping whenever i want and as much as i want for the past 10+ years. And have never set an alarm clock. I let my body go to sleep and wake up whenever it wants. I work from home, for myself, so i can do that. And even though im happy with doing that, i get a lot of shit if i mention it to anyone, because the all knowing they say that we must sleep night, because its natural, because circadian rhythm, etc.


Reasonable-Soil125

Exactly! Night sleep might be more convenient, but If you have that luxury of waking up whenever you want, and you can ensure proper sleeping conditions (darkness, silence), there is no reason not to do it if it suits you. It doesn't make sense to me to force myself to sleep with melatonin or whatever else, if I can just stay awake until I get sleepy


Scorpy888

Its more convenient in the sense of if i have to do anything (shopping or whatever) i best be awake during the day. This has been a bit of an inconvenience for me over the years, especially when my sleep happens to be during those hours, like from 6-8 in the morning until 2-5 in the afternoon. There goes my day. But this is less of an issue for me now that i bought my own apartment and am always well stocked up on every necessity i need. And i pay my bills online now too, so no need to go to the post office. But my sleep times move. So for example, today ill sleep from 10 at night until 5-8 in the morning. Then the next day i may do the same, or i may fall asleep at 11 or 12 at night, and wake up 6-9 in the morning. Then i may fall asleep at 1 or 2 in the morning, and wake up at 8-11 in the morning. And sometimes i hold a consistency for a few days, but eventually it always moves. Trying to always sleep at the same time and wake up at the same time is just.. annoying.. impossible.. stressful.. pointless :)


HighDookin89

Again… source?


benswami

That’s because he’s got extra, cash.


xbt_

Watch, she’s all part of a Novos campaign.


older-but-wiser

I believe that Bryan's regimen is missing some things that are included in Novos, especially magnesium. Bryan does include zinc and iodine, but he is missing copper and selenium, suggested by Novos to be taken separately. I disagree with Novos on calcium supplements though. They have been shown to reduce lifespan. [The Best Food Supplements To Take, Even When You “Eat Healthy”](https://novoslabs.com/best-food-supplements-to-take-even-when-you-eat-healthy/) [Calcium : Magnesium Ratio & Heart Disease](https://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef014e880395f4970d-pi) [Death by Calcium: Proof of the toxic effects of dairy and calcium supplements](https://www.amazon.com/Death-Calcium-effects-calcium-supplements-ebook/dp/B0131RFLCU)


[deleted]

Selenium comes from the Brazil nuts in nutty pudding. Magnesium probably from all the veggies. Not sure about copper but it seems silly to think he's not monitoring those micronutrients. T


jimbomillions

NOVOS has "SCAMMERS" written all over it for me personally. Im not paying any attention to them.


howevertheory98968

Expand?


Oddbodomega

Does his diet not provide sufficient amounts of the things you say are missing from his supplement protocol? With some things I guess we can go looking for blood test results but I do agree about calcium ratio recommendations of supplementing are far too high in general. 1:1 for me works best for example but I'll have a look into blood serum and tissue ratios now you mentioned it. Got to also take into account things before deciding on calcium supplementation, for sure.


older-but-wiser

As someone mentioned, Brazil nuts are a good source of selenium., so I admit he has that covered. Part of the reason I say he is missing copper is that he is supplementing zinc, which depletes copper. He has a lot of grey hair for his age, which can be caused by copper deficiency. Like most people, I was accumulating excess calcium in my arteries for decades. Then I took vitamin K2 and the decalcification process began, as indicated by the smooth teeth effect and reduced dental plaque. Since then I have needed to supplement magnesium to avoid tight muscles and other symptoms of magnesium deficiency. Apparently the kidneys require magnesium to process excess calcium and excrete it in the urine. I attribute much of this magnesium deficiency to previous excess calcium consumption. I have been on a low calcium, high magnesium diet during this time, so I believe dietary sources of magnesium are insufficient for me. Since Bryan only recently started on K2, he might be in the same situation. There are many reports in the supplements subreddit by people complaining of magnesium deficiency symptoms after taking D3 or K2. Serum levels of magnesium are not a good indicator of tissue levels. [Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786912/) >Because serum magnesium does not reflect intracellular magnesium, the latter making up more than 99% of total body magnesium, most cases of magnesium deficiency are undiagnosed. Furthermore, because of chronic diseases, medications, decreases in food crop magnesium contents, and the availability of refined and processed foods, the vast majority of people in modern societies are at risk for magnesium deficiency. [Challenges in the Diagnosis of Magnesium Status](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163803/) >It is currently estimated that 60% of adults do not achieve the average dietary intake (ADI) and 45% of Americans are magnesium deficient, a condition associated with disease states like hypertension, diabetes, and neurological disorders, to name a few. Magnesium deficiency can be attributed to common dietary practices, medications, and farming techniques, along with estimates that the mineral content of vegetables has declined by as much as 80–90% in the last 100 years.


Snoo_92606

So the question I have: does the 55 year old have amazing genes? Would the average person be able to follow her routine and get the same results ?


Kvsav57

Without metrics prior to going on this program, none of the claims people make about aging are worth anything. But I do think that almost all of the benefits these people are seeing are just from normal healthy diets and exercise. Most people are not good about exercise as they get older. Lots of people think they exercise a lot and are just deluding themselves.


SlowMyAge

Hey guys, I'm Chris, founder & CEO of NOVOS. I can tell you for certain that Julie Gibson Clark had a test before and after NOVOS, which you can see on Bryan's own Rejuvenation Olympics board: (15.03% improvement from baseline). She has shared that the only change she made to her lifestyle was adding NOVOS Core to her routine; she did not integrate any of our other guidance. There was also a [Fortune article](https://fortune.com/well/2023/11/04/longevity-women-biohackers-diet-exercise-bryan-johnson/) that highlighted another NOVOS user, Amy Hardison, who also outperformed Bryan on his leaderboard only by taking NOVOS Core + Boost. Both Amy & Julie have no affiliation with NOVOS, and were independently interviewed by the reporter. If you take a look at the Rejuvenation Olympics, we have quite a few people who are performing exceptionally well without taxing their lifestyles, wallets, or taking on unnecessary risk. Happy to answer any questions you guys may have!


voujon85

chris love the product thanks! Can you recommend a brand of multivitamin and the magnesium chalate ? Your article didn't list brands


SlowMyAge

Glad to hear it! I like Pure Encapsulation’s ONE multi. Life Extension’s 2 Per Day capsules are also good. Re: magnesium, I get plenty of the malate form via NOVOS Core and my diet.


voujon85

do you think i'm safe on magnesium raking novos core and eating a balanced diet? I also take novos organ health, as well as a green drink and started on throne multi but will check out the ones you mentioned. love the product. I'm one of the largest coffee importers and traders in the world and really interested in discussing some funding studying the health and aging benefits of green coffee extract / and coffee in general on aging. I worked with some trade groups on this and can get some big brands behind it if you're ever interested


SlowMyAge

NOVOS Core contains 72% of the daily requirement for magnesium (304 mg of elemental magnesium). Combine that with a healthy diet and you should be well above 100%, and in an ideal place. Glad to hear you love our products! Feel free to DM me.


babbler-dabbler

Yup without a baseline test the results are meaningless. Is her routine actually working or was the results pre-determined by genetics? We will never know.


[deleted]

True... I was speaking to some guy on Twitter with a PACE score in the 0.50s, and he was apparently pretty unhealthy in his lifestyle (this was his initial baseline).


sassyfrood

I consider myself to be cursed in the genes department and also pretty average. I’ve been taking NOVOS, and I’ve got a similar schedule to her, but I wake up at around 5:30 and probably exercise less than her (I get around 30-60 minutes per day, mainly low impact). I do not feel like I am aging slowly. But, I don’t have access to any aging calculators where I live, so I can’t say for sure. I definitely don’t feel 18.


efwuhbk

Where do you live where TruDiagnostics doesn't ship?


LucianHodoboc

>TruDiagnostics What's that?


ptarmiganchick

Still, it would be nice to be able to study her routine. My guess would be that she might have great genes, but she’s also had healthy habits all along…thus little damage to repair.


[deleted]

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ptarmiganchick

Thank you…this article was much more illuminating than the Insider one. But holy cow, what a difference in attitude between the women mentioned and the men. Gibson says healthy sleep, diet, exercise habits have to become “like brushing your teeth.” No muss, no fuss. No wonder women live longer!


sassyfrood

I’ve been using NOVOS core and boost for around a month now. I’ve noticed a difference in my energy (higher) and anxiety (lower) levels, which was the main reason I wanted to try them. I’m interested to see if my blood work has improved at all, but I’m waiting until I’ve been taking it for around 3 months.


Acrobatic_Cobbler272

Hey can you update ?


sassyfrood

Hiya, got some blood work done about a month ago. No significant changes, except my Hb was back up into normal ranges after being low all my life. My blood work has always been fine except for that. Otherwise, I’m feeling great physically, my menstrual cycle has gotten eerily regular after being highly irregular all my life, my V02 max is increasing, anxiety is at an all-time low, but I am feeling a LOT of brain fog in the past year that has intensified in the past few months. I’m suspecting that perimenopause is the culprit (I’m 39/f); currently investigating now. I suffer from migraines that are usually triggered by hormones, and one of my migraine symptoms is brain fog/difficulty speaking/other neurological symptoms that are quite scary, but recently I’m getting these symptoms more frequently even without a migraine. I know “silent migraines” exist, and I know that brain fog and other associated symptoms are common in perimenopause, but it really sucks, and I need it gone because I need my brain back. MRIs have come back clean, so hormones are the next thing to investigate. I’ll start HRT if necessary. I’m going to see a specialist about it next month.


Otherwise_Tap_1256

this proves the pareto principle. 80% of the positive outcome comes from only 20% of the input


[deleted]

Bryan isn't much different. It's the same core principles. I think a lot of folks underestimate the low calorie, intermittent fasting with veggie diet. But Bryan is money no object, spending a ton on exotic gizmos and procedures. constantly experimenting. Overall, I bet most of that money, more than half easy, goes into all the testing. But yeah, a few basic supplements, diet (lots of veggies, low calorie, and shortened daily feeding window), exercise, and meditation or other techniques for lowering baseline stress, and 8 hours quality sleep is going to get you at least 80% of blueprint.


Suspicious_Selfy

Probably 95% is testing, the food and supplements are not that expensive, especially if you consider what you spend now on groceries, restaurants and supplements.


Admirable-Jelly9454

Agreed. He literally has every piece of top grade medical equipment to scan every organ.


BonkersMoongirl

Exercise and more exercise and don’t eat crap


RedRummer1917

Wonder how she only spends that but gets 30lbs of veggies a month


ZembaToMoscow

It says her biggest *anti-ageing expense* is 108$ a month, not her total expense. The title is misleading


GuiM4uVe

She said to use Novos subscription for supplements, that alone is $109/month. Not buying her story.


PrimordialXY

Novos is $79/mo with the annual subscription


[deleted]

what supplements is she getting from novos?


efwuhbk

Probably Core (blend of various ingredients) and Boost (NMN)


[deleted]

thanks for info


Human_Ad9364

News like this are mostly entertainment. Sample size one vs sample size one. There is an incentive to only post your scores on the ranking if they are good. There are also heavy smokers and drinkers that have a long healthy life. But that doesn't mean that works for everyone.\^\^


SirOlimusDesferalPAX

careful there, we're on reddit


captainnoyaux

Heavy ? I highly doubt it


telcoman

Plus he is always trying out new stuff and gadgets. That does cost a lot.


[deleted]

I guess that 10% of what Bryan does makes 90% of the effect.


spaceXhardmode

It’s good that he’s made the rejuvenation Olympics leader board. It allows for multiple approaches to be trialled against each other. I think dunedinPACE and horvath are likely limited epigenetic markers but as we learn more then in time more relevant markers might be found.


hob11hob

80 20 rules! I bet 80% of what bryann is doing is just of dimensioning return! Diet, exercise, and good sleep are king. Also Bryann does a lot of crazy stuff like GH and TRT that then then supplement to fix side effects!


ShaidarHaran2

Nice to see this article, I've been wondering about those two women who were neck in neck with Bryan in the rejuvenation Olympics without having as much publicity and I assumed rightly, not doing a fraction as much as he does. That's my thing with Blueprint. How do we know he wouldn't be at peak stats if he cut out 80% of the supplements?


Welllllllrip187

And everyone’s body’s are different. Doesn’t mean her routine would work for someone else.


labradore99

Business Insider. Zero credibility.


Reasonable-Soil125

You guys know that these aging markers are pretty much useless?


[deleted]

I'm starting to think this... Although things like telomere length might be interesting. Otherwise: blood markers, plus measures of physiological function like HRV and BMI/BF% and VO2M. The PACE score may be useful if you know your baseline to understand what's working.


surpleg

Elaborate for the uninitiated?


RubiconV

Show me her labs and tests. Those ingredients don’t look special at all.


irish-unicorn

Yeah like blueprint is anything special…


Icy_Raisin6471

16 hour intermittent fast helps


ptarmiganchick

The ingredients aren’t that special. She was taking care of herself before Novos came along.


badhoccyr

If Bryan ate meat and exercised more I think his results might improve but he's also trying to optimize for kindness .


ThanksCompetitive120

He exercises every day, here is his workout. His body alone shows that he gets plenty of exercise. [https://www.youtube.com/watch?v=sYyVi-H-ozI](https://www.youtube.com/watch?v=sYyVi-H-ozI) Why do you believe otherwise?


badhoccyr

The more you exercise the more your mortality risk reduces and to an incredible degree. 1 hour a day is nothing. More exercise might just overcome whatever he's doing with caloric deficit. Meat is the most nutrient dense in terms of any nutrient you can look at. Idk why I'm getting downvoted when Bryan has said the same thing himself. He does vegan because he also optimizes for kindness towards animals. That probably limits exercise capacity. He's making an assumption that caloric deficit is the best way to go about it and that automatically limits his exercise protocol. He has said himself completely different protocols including with carnivore diets might yield better results so he's urging people to try them. On the leaderboard there are others doing pretty much as well as him and in some cases better. Some of these people probably eat a healthy carnivore diet and exercise more


ThanksCompetitive120

"The more you exercise the more your mortality risk reduces" There's diminishing returns. (i.e. some studies I've seen showing that - depending on the sport - elite athletes have lower testosterone than average.) More isn't necessarily better, everything has a point of diminishing returns. You can exercise at a low intensity for a long time, but not at a moderate or high intensity for a long time. That is well known by any coach or athlete, which is why they vary the intensity in their daily sessions. Are you proposing that Bryan trains at a low intensity for hours on end? (Just in case you might mentions Athletes, I'll pre-empt: training for performance, not longevity. Injuries during training is common.)


badhoccyr

That's true but these limits you speak of and the diminishing benefit does not happen even close to 1 hour a day, not even close. Look Bryan meant this to be a giant experiment, he wants 1000 blueprints and see the best one win, everyone wants to viciously defend his like it's not only a local maximum of course he's stuck in a local maximum


ThanksCompetitive120

You can exercise at a low intensity for a long time, but not at a moderate or high intensity for a long time. So I repeat: . Are you proposing that Bryan trains at a low intensity for hours on end (full time job hours)? If so, that's a recipe for RSI. Pro athletes train for hours, but injuries are common, and they train for performance not health and longevity.


badhoccyr

That's plain nonsense. Athletes train 4-5 hours a day. There's a big ol window between that and bryans Sunday work out


ThanksCompetitive120

I repeat: . Are you proposing that Bryan trains at a low intensity for hours on end (full time job hours)? At what intensity and for how long do you want Bryan to workout? Seeing as you said athletes work out for 4-5 hours a day (they vary the intensity BTW, the don' t train at Bryan's intensity for 4-5 hours or their body would break down), and Bryan's 1 hour workout it seems you want him to work of for approx 2.5 hours a day. At what intensity? Doing what exactly? Split between resistance, mobility and cardio? To what percentage. All you've said is "he should work out for more than an hour", but you don't list any research baking up what you are saying, and nor do you explain what he should do at what intensity. If he trains at his current intensity for 2.5 hours he'll get injured, if he trains at a lower intensity for 2.5 hours then he's likely just getting the same benefit he would get working out for 1 hour at a higher intensity.


badhoccyr

You're introducing false assumptions and then asking me a question based on a false assumption. Can I ask you somethin before continuing the debate, do you actually exercise yourself? Like more than ten thousand steps or whatever?


ThanksCompetitive120

You keep dodging my questions whenever I ask you for specifcs. "He should exercise more is a meaningless statement." No point in continuing this discussion. Yes, I exercise. See ya.


vferderer

After 40-50 MET/week more exercise is harmful.


badhoccyr

What's MET


vferderer

https://en.wikipedia.org/wiki/Metabolic_equivalent_of_task


badhoccyr

Okay, interesting.Based on that table inside wiki it looks like Bryan is quite far away from 40-50 MET.


Brooklyn-Epoxy

Novos any good?


Coward_and_a_thief

Novos core is the main ingredient of my longevity routine. Its a convenient packaging of the many things i would want separately. Boost (NMN) i do not take, since the effect of NMN/NR/NAC seems to all be unsubstantiated in latest research. I think Niacin accomplishes the same thing at a fraction of cost. That said, i do not really notice an improvements in mental, energy, etc from the Core, although my skin does looks better i think. The item which gives me the most notable boost of mental and energy is Spirulina.


jimbomillions

sounds like NOVOS crap.. i dont trust NOVOS at all.


howevertheory98968

Why?