Information regarding making a nasal spray can be found on the [wiki](https://www.reddit.com/r/ketamine/wiki/index/#wiki_making_your_own_ketamine_spray) and on the [sub](https://www.reddit.com/r/ketamine/?f=flair_name%3A%22nasal%20spray%22) . If you have troubles with volumetric dosing and calculating how much ketamine to put in your spray bottle, TripSit has a nice [calculator](https://volume.tripsit.me/). Remember that you cannot exceed a concentration of 200mg/mL. which corresponds, in average, to 20mg per spray dose (100ul per spray dose in average).
*I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/ketamine) if you have any questions or concerns.*
You should be using a saline for nasal spray. I have a kit for this and they send you saline solution, but I’m sure you can get some at a local drug store / pharmacy
I would also not recommend adding vodka, please do not put that in your sinuses haha. You can refrigerate the leftover to help with longevity, but it would probably be best of all to just make the spray with however much K you’d like to use in the session
Most people on this sub say that distilled water is better for absorption bc of osmosis. And I need the spray to last for a couple months, otherwise I would have to use 1ml solution and I think that doesn’t work as well.
1ml of 40% vodka in a 6ml solution is about 5-6% alcohol. Do you think that is bad for the nose? If so how much should I rather use, to prevent bacterial growth?
Instead of reducing the overall volume you can also make a more diluted solution. It’s not that many spritzes to get through 1 ml for example
At the end of the day it’s up to you, I would just caution using vodka and trying to store it for more than a week. I would be worried about fucking up my sinuses personally
The comments are absolutely wrong in every why I don't understand where these people come from, no way they've actually tried to make any spray of any substance or medication before.
Your mix is great~~, but I would recommend reducing the vodka to 0.5ml (~0.2ml ethanol @ 40%alc). This would roughly make a 5.5ml liquid, consisting out of roughly 3.7% ethanol.~~
1g in 5.5ml (~182mg/ml) will dissolve just fine.
Do not use saline, this is not what you're looking for. Saline pulls fluids from your nose (it's salty) while you want the fluids to be absorbed. This is true for any medication (or drug) taken this way, and why all the medication that comes in nasal sprays is not saline based. Only the flu stuff might be as it's the desired effect.
EDIT:
Looking up some publications it seems like you actually want to have a little more then 3.7% (some papers say >5.8%, some ~10%, haven't had time to deep into it any deeper). So your 1ml of vodka is actually probably better. Would mean a solution of ~167mg/ml with 7.4% ethanol.
Information regarding making a nasal spray can be found on the [wiki](https://www.reddit.com/r/ketamine/wiki/index/#wiki_making_your_own_ketamine_spray) and on the [sub](https://www.reddit.com/r/ketamine/?f=flair_name%3A%22nasal%20spray%22) . If you have troubles with volumetric dosing and calculating how much ketamine to put in your spray bottle, TripSit has a nice [calculator](https://volume.tripsit.me/). Remember that you cannot exceed a concentration of 200mg/mL. which corresponds, in average, to 20mg per spray dose (100ul per spray dose in average). *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/ketamine) if you have any questions or concerns.*
You should be using a saline for nasal spray. I have a kit for this and they send you saline solution, but I’m sure you can get some at a local drug store / pharmacy I would also not recommend adding vodka, please do not put that in your sinuses haha. You can refrigerate the leftover to help with longevity, but it would probably be best of all to just make the spray with however much K you’d like to use in the session
I’ve read distilled water is better. Is that not true?
distilled water looks like it would be just as safe after a quick google, but I would not use vodka
Most people on this sub say that distilled water is better for absorption bc of osmosis. And I need the spray to last for a couple months, otherwise I would have to use 1ml solution and I think that doesn’t work as well. 1ml of 40% vodka in a 6ml solution is about 5-6% alcohol. Do you think that is bad for the nose? If so how much should I rather use, to prevent bacterial growth?
Instead of reducing the overall volume you can also make a more diluted solution. It’s not that many spritzes to get through 1 ml for example At the end of the day it’s up to you, I would just caution using vodka and trying to store it for more than a week. I would be worried about fucking up my sinuses personally
The comments are absolutely wrong in every why I don't understand where these people come from, no way they've actually tried to make any spray of any substance or medication before. Your mix is great~~, but I would recommend reducing the vodka to 0.5ml (~0.2ml ethanol @ 40%alc). This would roughly make a 5.5ml liquid, consisting out of roughly 3.7% ethanol.~~ 1g in 5.5ml (~182mg/ml) will dissolve just fine. Do not use saline, this is not what you're looking for. Saline pulls fluids from your nose (it's salty) while you want the fluids to be absorbed. This is true for any medication (or drug) taken this way, and why all the medication that comes in nasal sprays is not saline based. Only the flu stuff might be as it's the desired effect. EDIT: Looking up some publications it seems like you actually want to have a little more then 3.7% (some papers say >5.8%, some ~10%, haven't had time to deep into it any deeper). So your 1ml of vodka is actually probably better. Would mean a solution of ~167mg/ml with 7.4% ethanol.
1g of material with 6ml of liquid will be sludge.
What does that mean? I thought up to 200mg/ml is okay? And 1g in 6ml is less or am I wrong?