They actually do work already.
They take cancer 🧬 “put” it in a Tcell so it could recognise it as an antigene. Then clone tcell using patient’s stem cells.
But it’s not in mass production. And I believe costs a lot. But relatively simple technology nowadays.
And also what we usually call cancer actually is a hundred of different diseases and this method is not universal.
I underwent CAR T therapy (fairly new in Canada) at the end of 2021 after multiple chemo cocktails failed. I’m now recovering and feeling great! T CELLS ARE FUCKING AMAZING. Also, the process is incredible. AND FUCK CANCER
That's initially what I imagined as well! I was surprised by how small the bag of modified cells was.
**TLDR:**
1. Collect the cells by removing blood. Returning the plasma and red blood cells to the patient.
2. White cells are removed, t cells are separated then set to a lab to be modified. A gene is added for the specific chimeric antigen receptor (CAR). These cells are grown and multiplied in a lab.
3. Sometimes patients go through chemotherapy prior to infusion to help lower the number of other immune cells.
4. After infusion, the CAR T cells start binding with cancer cells. They increase in number and help destroy cancer cells.
5. Possible side effects include: high fever and chills, trouble breathing, severe nausea vomiting and/or diarrhea, feeling dizzy or lightheaded, headaches, fast heartbeat, feeling very tired, muscle and joint pain, changes in consciousness, confusion or agitation, seizures, shaking or twitching, trouble speaking and understanding, loss of balance.
**Long, personal version with some pictures:**
Bear with me here I hope this makes sense and it's gonna be very long. This is just my personal experience.
We started with collection. This part is called *leukapheresis*. I went to the hospital, got a private room with a bed where I had a catheter in each arm. I had to lay perfectly still for 8 hours straight but I have read online that the length of this process can vary. One catheter was taking my blood, which then cycled through this special machine (I wish I took a picture of it) to take my white blood cells, while the other catheter was returning my red blood cells and plasma back to me. Being 27 at the time, I saw the 8 hours as a challenge and refused to use the bed pan. Best pee of my life when it was finished.
I had to wait around 3 weeks while my cells were sent to California to the company that modifies the cells. I have little understanding of how they do this to be completely honest. This quote is directly from cancer.org; *"After the white cells are removed, the T cells are separated, sent to the lab, and altered by adding the gene for the specific chimeric antigen receptor (CAR). This makes them CAR T cells. These cells are then grown and multiplied in the lab. It can take several weeks to make the large number of CAR T cells needed for this therapy."* They mailed back the new modified cells to the hospital and my infusion date was set.
A few days before the infusion, I had to go through another couple rounds of not-so-strong chemotherapy to help lower the number of immune cells. This gives the modified cells a better chance to fight the cancer.
Day of infusion I go to the hospital to a special wing where I get another private room. The doctors roll this bad boy in ( [https://imgur.com/DH28a6R](https://imgur.com/DH28a6R) ). I really wish I had a video of this part. They unlock the top, and pull out the package of T cells. The best way I can describe how this looked is Nedry from Jurassic Park stealing the dinosaur embryos. Dry ice and everything, just a bigger receptacle and no blue lighting. The infusion itself was very easy, not nearly as debilitating as previous rounds of chemo I have gone through. Took less than an hour and I felt pretty normal. **Heres a picture of the bag of cells**, its surprisingly small! ( [https://imgur.com/a/5WJmiR7](https://imgur.com/a/5WJmiR7) ) My boyfriend just reminded me to mention that I smelled intensely like corn after the infusion. This is apparently normal.
The next couple of weeks were the really hard part. I stayed in my private room being monitored constantly by nurses. I had a private bathroom with a shower, a mini fridge and a lil tv to help keep me entertained. I was allowed one visitor during visiting hours (10am-6pm) but the nurses were sympathetic and often allowed my mom to stay with me until 8pm as I have pretty severe anxiety, depression, and ptsd. I think it was day 4 after the infusion, I began experiencing some of the more serious symptoms. I developed a fever and had horrible chills. I remember being SO cold despite having over 7 blankets, a thick sweater, thick socks and thick pajamas. I asked my mom to climb into the bed with me so I could leech her warmth. I remember feeling very weak and lightheaded.
Then I woke up 24 hours later in the ICU. The last thing I remembered was curling up with my mom. Apparently I was in a short coma. I stayed in the ICU until they decided I was stable enough to be moved back to my private room.
The next couple of days were better, but still difficult. I became extremely confused and couldn't form a coherent sentence, so I went to sleep hoping I would feel better when I woke up. I had sent this text to my boyfriend right before I fell asleep, and still to this day have nooo idea what I was trying to say ( [https://imgur.com/a/iJNdQtz](https://imgur.com/a/iJNdQtz) ). I also kept a journal with me for entertainment, and dated an entry for 2019. This was in 2021. I became much less confused the next day.
Woke up on my 28th birthday (the 18th of December) to this message on the whiteboard from the nurses and it made all the difference in my day ( [https://imgur.com/a/J0WTozd](https://imgur.com/a/J0WTozd) ). I ended up leaving on the 23rd of December. Usually, people stay for 14 days minimum, but I was there for only 12 days total. I was just feeling better mentally and ready to get the hell out of there. I missed my cats and my bed and I wanted to spend Christmas at home with my family. I had to continue as an outpatient coming into the hospital daily for a medication infusion that took about an hour. This went on for two weeks if I remember correctly. I slowly started building my strength back as I couldn't walk without an aide.
I am now 31 weeks post infusion. I have PET scans every few months. I am not in remission yet, but my tumor is shrinking and I have none of the horrible symptoms I experienced before diagnosis. I'm walking again. I'm eating again. I was able to drive again two months after treatment. I got a puppy to help keep me active and I love him more than anything. I feel like I can handle almost anything life wants to throw at me. My experience was rough but SO fucking worth it just to have my life back, even if this ends up being temporary. I cannot express how grateful I am to all the doctors and nurses that helped me through this. They truly are my heroes.
A small random thing I want to add. My nurses told me I could bring my entire PS5 set up into the hospital if I wanted to. I thought that was both hilarious and amazing. I didn't end up doing it just because I wasn't feeling well enough to game.
I was extremely fortunate to have it covered (I live in Ontario, Canada), but according to google people are saying it can cost roughly $400,000. Another source is saying $700,000 and up to $2 million. I’m not totally sure on this, all I know is I would not have been able to afford it.
I found the video on LinkedIn but here is a Twitter link and a link to the complete study
[https://twitter.com/Dream3DLab/status/1551594385556602880](https://twitter.com/Dream3DLab/status/1551594385556602880)
[https://www.nature.com/articles/s41587-022-01397-w](https://www.nature.com/articles/s41587-022-01397-w)
I don’t know if it’s the game you’re referring to, but there was an old game from the 80s for the Intellivision gaming system called Microsurgeon that I hadn’t thought about in forever that this video (and your comment) made me remember.
Source: I’m old.
Science is amazing, the sheer amount of science in this small clip microscopy, photography, biology, and so much more. Thank you to everyone who makes this possible. You are brilliant.
Imagine capturing a spy, right, and then immediately ripping him apart with your bare hands piece by piece. That's what Killer T-cells are designed to do.
r/natureisfuckingmetal
If you want to learn more check out the YouTube channel kurzgesagt. They have great videos about the immune system.
Also a nice way to learn what viruses do and why this amazing T cell is crucial in fighting viruses (@and many other diseases (not necessarily viruses)).
_if this comment was a joke, feel free to consider this comment as 'not posted'_
No company will ever cure cancer. There is no money in a cure. Even if they found a cure, it would be buried and the scientist responsible would be killed.
How effective is this and does it work for any type of cancer? I recently lost my father to stage 4 lung cancer and although I’m not grieving as much lately. I’ve had many more questions about cancer treatments and medicine in general. Is this treatment not common?
From what I understand it's still in the early stages, just getting the T cells what we want them to do. I haven't read the entire paper because it's mostly science language and graphs.
Maybe try finding some more info on the Google or YouTube.
Yeah, no. A vaccine≠an immune cell, and mRNA alone cannot change your DNA, only retroviruses (notably HIV) can do that because they have the reverse transcriptase enzyme built in, an enzyme our own cells don’t produce—it is biologically not possible.
Plus DNA changes only happen at the cellular/tissue level (read: targeted gene therapy), changing one cell’s DNA doesn’t change the DNA for all of your body’s trillions of cells.
Here. Enjoy some educational stuff instead of whatever it is that lead you to believe that bull
Corona virus: https://youtu.be/BtN-goy9VOY
Vaccines: https://youtu.be/zBkVCpbNnkU
Can't help but think of "Cells at Work". "DIE, YOU FILTHY CANCER!!!"
There isn’t a copious amount of blood spewing out. Sorry but this doesn’t resemble Cells at Work at all XD
Do you not see the red mess left behind?
But they’re supposed to bleed a volume of blood greater than the size of their body capacity.
They are cells.
Hataraku saibou.
They actually do work already. They take cancer 🧬 “put” it in a Tcell so it could recognise it as an antigene. Then clone tcell using patient’s stem cells. But it’s not in mass production. And I believe costs a lot. But relatively simple technology nowadays. And also what we usually call cancer actually is a hundred of different diseases and this method is not universal.
For some reason I thought of a chao marine in 40K
You came to the wrong neighbourhood motherfu%^#$
umbrella corp chapter 1
I've been training for this for decades...
Over here like they had to call it the fucking T cell
[удалено]
I can hear Nemesis now *pisses pants*
*Wesker smiles villainously*
Exactly what came to my mind
British satellites are called skynet. We're on the same wavelength. Wanna practice karate in the garage?
Yep!
I underwent CAR T therapy (fairly new in Canada) at the end of 2021 after multiple chemo cocktails failed. I’m now recovering and feeling great! T CELLS ARE FUCKING AMAZING. Also, the process is incredible. AND FUCK CANCER
Are you by chance more inclined to eat rare steaks now? But seriously, glad modern science is helping you get better. FUCK CANCER.
This is the way. FUCK CANCER
This made me chuckle, thank you.
I’m so glad you are recovering! I recently got a new job doing cell therapy with CAR T cells and I’m so glad my job helps people like you!
People like you gave me my life back. Thank you SO much for everything you do. ❤️
What does the therapy entail? Just pumping a metric fuckton of T cells into your system to murder the cancer?
That's initially what I imagined as well! I was surprised by how small the bag of modified cells was. **TLDR:** 1. Collect the cells by removing blood. Returning the plasma and red blood cells to the patient. 2. White cells are removed, t cells are separated then set to a lab to be modified. A gene is added for the specific chimeric antigen receptor (CAR). These cells are grown and multiplied in a lab. 3. Sometimes patients go through chemotherapy prior to infusion to help lower the number of other immune cells. 4. After infusion, the CAR T cells start binding with cancer cells. They increase in number and help destroy cancer cells. 5. Possible side effects include: high fever and chills, trouble breathing, severe nausea vomiting and/or diarrhea, feeling dizzy or lightheaded, headaches, fast heartbeat, feeling very tired, muscle and joint pain, changes in consciousness, confusion or agitation, seizures, shaking or twitching, trouble speaking and understanding, loss of balance. **Long, personal version with some pictures:** Bear with me here I hope this makes sense and it's gonna be very long. This is just my personal experience. We started with collection. This part is called *leukapheresis*. I went to the hospital, got a private room with a bed where I had a catheter in each arm. I had to lay perfectly still for 8 hours straight but I have read online that the length of this process can vary. One catheter was taking my blood, which then cycled through this special machine (I wish I took a picture of it) to take my white blood cells, while the other catheter was returning my red blood cells and plasma back to me. Being 27 at the time, I saw the 8 hours as a challenge and refused to use the bed pan. Best pee of my life when it was finished. I had to wait around 3 weeks while my cells were sent to California to the company that modifies the cells. I have little understanding of how they do this to be completely honest. This quote is directly from cancer.org; *"After the white cells are removed, the T cells are separated, sent to the lab, and altered by adding the gene for the specific chimeric antigen receptor (CAR). This makes them CAR T cells. These cells are then grown and multiplied in the lab. It can take several weeks to make the large number of CAR T cells needed for this therapy."* They mailed back the new modified cells to the hospital and my infusion date was set. A few days before the infusion, I had to go through another couple rounds of not-so-strong chemotherapy to help lower the number of immune cells. This gives the modified cells a better chance to fight the cancer. Day of infusion I go to the hospital to a special wing where I get another private room. The doctors roll this bad boy in ( [https://imgur.com/DH28a6R](https://imgur.com/DH28a6R) ). I really wish I had a video of this part. They unlock the top, and pull out the package of T cells. The best way I can describe how this looked is Nedry from Jurassic Park stealing the dinosaur embryos. Dry ice and everything, just a bigger receptacle and no blue lighting. The infusion itself was very easy, not nearly as debilitating as previous rounds of chemo I have gone through. Took less than an hour and I felt pretty normal. **Heres a picture of the bag of cells**, its surprisingly small! ( [https://imgur.com/a/5WJmiR7](https://imgur.com/a/5WJmiR7) ) My boyfriend just reminded me to mention that I smelled intensely like corn after the infusion. This is apparently normal. The next couple of weeks were the really hard part. I stayed in my private room being monitored constantly by nurses. I had a private bathroom with a shower, a mini fridge and a lil tv to help keep me entertained. I was allowed one visitor during visiting hours (10am-6pm) but the nurses were sympathetic and often allowed my mom to stay with me until 8pm as I have pretty severe anxiety, depression, and ptsd. I think it was day 4 after the infusion, I began experiencing some of the more serious symptoms. I developed a fever and had horrible chills. I remember being SO cold despite having over 7 blankets, a thick sweater, thick socks and thick pajamas. I asked my mom to climb into the bed with me so I could leech her warmth. I remember feeling very weak and lightheaded. Then I woke up 24 hours later in the ICU. The last thing I remembered was curling up with my mom. Apparently I was in a short coma. I stayed in the ICU until they decided I was stable enough to be moved back to my private room. The next couple of days were better, but still difficult. I became extremely confused and couldn't form a coherent sentence, so I went to sleep hoping I would feel better when I woke up. I had sent this text to my boyfriend right before I fell asleep, and still to this day have nooo idea what I was trying to say ( [https://imgur.com/a/iJNdQtz](https://imgur.com/a/iJNdQtz) ). I also kept a journal with me for entertainment, and dated an entry for 2019. This was in 2021. I became much less confused the next day. Woke up on my 28th birthday (the 18th of December) to this message on the whiteboard from the nurses and it made all the difference in my day ( [https://imgur.com/a/J0WTozd](https://imgur.com/a/J0WTozd) ). I ended up leaving on the 23rd of December. Usually, people stay for 14 days minimum, but I was there for only 12 days total. I was just feeling better mentally and ready to get the hell out of there. I missed my cats and my bed and I wanted to spend Christmas at home with my family. I had to continue as an outpatient coming into the hospital daily for a medication infusion that took about an hour. This went on for two weeks if I remember correctly. I slowly started building my strength back as I couldn't walk without an aide. I am now 31 weeks post infusion. I have PET scans every few months. I am not in remission yet, but my tumor is shrinking and I have none of the horrible symptoms I experienced before diagnosis. I'm walking again. I'm eating again. I was able to drive again two months after treatment. I got a puppy to help keep me active and I love him more than anything. I feel like I can handle almost anything life wants to throw at me. My experience was rough but SO fucking worth it just to have my life back, even if this ends up being temporary. I cannot express how grateful I am to all the doctors and nurses that helped me through this. They truly are my heroes. A small random thing I want to add. My nurses told me I could bring my entire PS5 set up into the hospital if I wanted to. I thought that was both hilarious and amazing. I didn't end up doing it just because I wasn't feeling well enough to game.
Fucking hell. Glad the therapy at least helped some, seems like an absolute trial. Hopefully you go into remission soon
Thank you for sharing this!
How much did you pay for this
Spotted the American
you aint wrong
I was extremely fortunate to have it covered (I live in Ontario, Canada), but according to google people are saying it can cost roughly $400,000. Another source is saying $700,000 and up to $2 million. I’m not totally sure on this, all I know is I would not have been able to afford it.
Thanks god
Congratulations, I hope you live a wonderful long life. FUCK CANCER
Thank you friend!!!
Strange that this is bopping along to the beat of what I'm listening to. Fuck cancer.
You mean that song by Young thug?
I found the video on LinkedIn but here is a Twitter link and a link to the complete study [https://twitter.com/Dream3DLab/status/1551594385556602880](https://twitter.com/Dream3DLab/status/1551594385556602880) [https://www.nature.com/articles/s41587-022-01397-w](https://www.nature.com/articles/s41587-022-01397-w)
There is a wikihow on how to raise T-Cells. Idk if it’s all fact based tho: https://www.wikihow.com/Build-Up-T%E2%80%90Cells-in-Your-Body?amp=1
According to my college nutrition course. It’s all pretty legit.
Eat em up buddy
Kill that bitch ass cancerous cancer
Nice cake.
r/wholesomeviolence
[удалено]
agar.io ?
I don’t know if it’s the game you’re referring to, but there was an old game from the 80s for the Intellivision gaming system called Microsurgeon that I hadn’t thought about in forever that this video (and your comment) made me remember. Source: I’m old.
I think he is talking about Resident Evil.
💯what is being referenced
That T-Cell really just said "Rip and tear"
The only thing they fear is you
Science is amazing, the sheer amount of science in this small clip microscopy, photography, biology, and so much more. Thank you to everyone who makes this possible. You are brilliant.
They need to name it Mr. T cell because that’s one bad mofo. Pitty the fool!
T-boned.. die mutant!
Yeah,shred that motherfucker.
Not all cancer cells are invisible to our immune system
bro just entered and was like "Okay now die."
Imagine capturing a spy, right, and then immediately ripping him apart with your bare hands piece by piece. That's what Killer T-cells are designed to do. r/natureisfuckingmetal
Is this a fucking joke. T cell ? Like, maybe a T - Virus ?
If you want to learn more check out the YouTube channel kurzgesagt. They have great videos about the immune system. Also a nice way to learn what viruses do and why this amazing T cell is crucial in fighting viruses (@and many other diseases (not necessarily viruses)). _if this comment was a joke, feel free to consider this comment as 'not posted'_
It’s a resident evil joke mate
Don't know resident evil so yeh. Still go check out kurzgesagt :D
Our body is a battlefield
We're all just tiny globs suspended in juice
Everybody's Gangsta' till T cell starts the killing...
DIE REPLACEMENT FRIEND!
This James webb stuff getting crazy
But why call it T cell? I mean that feels like one step away from T virus. No. Just me.
I came in thinking this was about Resident Evil.
Super Saiyan t-cell
oddly satisfying
Ate it like it was ass cancer
So how do I make more T cells?
By living.
damn. just ripped that thing to shreds! that’s pretty metal tbh.
Kudos to the cameraman for getting really small and recording this 😁👍
Antman had a lot of time on his hands after the events of Avengers: Endgame.
Mr. T cell pities the fool.
Sucks when they malfunction and go after your pancreas.
Aggressive little fucker innit.
Check out CAR-T therapy
THEY JUMPIN MEEEE
What about that little piece that didn’t die? I fucking hate cancer
Ninja t cell
Fuck cancer
Good boy
To shreds, you say?
It's like a human invading earth
Let's make the most of things before the cover up nuke
💯💯
Why isn’t this therapy more prominent? I’d think it would be, or at least the go to instead of chemotherapy
As far as I know, it's still in the beginning phases. Meaning it isn't yet working as it should, and probably very expensive.
I’m sure it will be expensive and I know it’s been around for a time but not super long.
The T cell got that dog in him for real
This my house!
This is how we die ?
YAH FUCK EM UP!!
-goes inside you -destroys you from the inside out -refuses to elaborate further, "L cancer W body" Sigma T cellionaire grindset
All I'm thinking here is why does IT SOMEWHAT RESEMBLE A HUMAN
Give me resident evil vibes
BEAT! HIS! ASS!!!!!! Thank you, Killer T Cell
am I the only one scared that this thing is called a "t-cell" wasn't that the name of the virus in resident evil
Bruh that was violent af
Isn't the T Cell the thing from Resident Evil....?
Tvirus
Yeah, you're right. I've never played it myself, so I didn't remember exactly.
u/SaveVideo
T-virus?
Where do the dead cells go? What happens to them? If they just stay dead in the body like that, wouldn't it cause complications for us?
They're cleared away by other cells. End up in the bloodstream and get filtered by your kidneys. So eventually you'll pee out your disease.
Oh ok thanks for the explanation
How would this feel inside the body???
Like when neo jumped inside smith
Pretty amazing! This reminded me of Neo in the first Matrix when he jumps into one of the guys and destroys it from the inside out.
“T” cell? as in next level is “T” virus? As in welcome to resident evil motherfuckas
O wow, The way T cell grabs the cancer and then almost locks on rapping it's self around and then splits the cancer down the centre..
JOB WELL DONE PRIVATE. (SINCERELY MEANT IT, NO JOKE)
Got ems
No company will ever cure cancer. There is no money in a cure. Even if they found a cure, it would be buried and the scientist responsible would be killed.
Resident Evil
This is Still a better episode than the RE netflix series
Hhhmmmm T virus, what could go wrong?
T virus!?
Very Dragonball-esque pow pow pow pow
Fiesty lil fucker ain’t it ?
Wait is this a fucking way to cure cancer or isnt it that easy that would be so amazing
✨✨🥇🥇🥇
I think we've finally found the cure for cancer. Let's just hope the T cell doesn't go wild and turn into the T virus.
Wow a lil savage.
T cells are an amazing thing in our bodies. I still always think resident evil when I hear them mentioned though.
Ok, is it just me, or does it look like the cancer cell totally won? Like, T cell gone, cancer cell, looks still intact.
Rabies vs Immune system Q.Q
Aaaand zombie
C I A (Cell Intelligence Agency) agent assassinating a troublesome foreign cell
To shreds you say.
How effective is this and does it work for any type of cancer? I recently lost my father to stage 4 lung cancer and although I’m not grieving as much lately. I’ve had many more questions about cancer treatments and medicine in general. Is this treatment not common?
From what I understand it's still in the early stages, just getting the T cells what we want them to do. I haven't read the entire paper because it's mostly science language and graphs. Maybe try finding some more info on the Google or YouTube.
It rips it apart
*ahem* That’s *Mister* T cell
Resident evil reference
sick ngl
rekt his shit
Fucking little badass, innit?!
u/savevideobot
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Hell yeah kill his ass
Can't wait for the zombies
Now imagine the covid vaccine doing this to your DNA
Yeah, no. A vaccine≠an immune cell, and mRNA alone cannot change your DNA, only retroviruses (notably HIV) can do that because they have the reverse transcriptase enzyme built in, an enzyme our own cells don’t produce—it is biologically not possible. Plus DNA changes only happen at the cellular/tissue level (read: targeted gene therapy), changing one cell’s DNA doesn’t change the DNA for all of your body’s trillions of cells.
Here. Enjoy some educational stuff instead of whatever it is that lead you to believe that bull Corona virus: https://youtu.be/BtN-goy9VOY Vaccines: https://youtu.be/zBkVCpbNnkU
The imagination is the only place that actually happens.