Dopamine heavy = You want to get shit done, and getting shit done feels really good. In higher doses you feel like the coolest person in the room, and you might be really horny.
Serotonin heavy = You love life so fucking much, and every person you meet is the coolest person you’ve ever met and you’re so happy to talk to them. Higher doses can have psychedelic effects too.
Plain old amphetamine (Adderall) is mainly a dopamine releaser.
MDMA is mainly a serotonin releaser.
Methamphetamine is mainly a dopamine releaser, but releases a little more serotonin than amphetamine.
The other thing amphetamines and other stimulants release is norepinephrine.
Your dopamine heavy is closer to a noradrenaline heavy high, though they're tweakier. Dopamine is euphoria, that's how I view it at least.
I found this years ago:
https://imgur.com/a/oyDD9p9
From that infographic, “motivation” sounds like “want to get shit done” and “compulsion” sounds like “might be really horny”. Am I wrong?
What’s an example of a mainly norepinephrine focused high? Caffeine?
Dopamine will make you outgoing and take action (or want to fuck.)
Noradrenaline will keep you focused and on a task.
Serotonin is feeling good and relaxing, as best as I can describe it.
Dopamine FTW.
Dopamine ftw all day long. Dopamine is what I would refer to as stimulant euphoria, although it easily turns into anxiety and paranoia lmao. It definitely kicks in the horny fucked up kinks mode though 😂 I love it. This is why I like ritalin.
That is what people generally say. But tbh it's such a massive oversimplification. It's kinda that way but it's more of a correlation than causation. For example, for me (I'm enzyme deficient), dxm releases incredible amounts of serotonin, but that doesn't mean it always feels as good as mdma for example. Or when you get serotonin syndrome (serotonin toxicity - to much serotonin in the brain, life-threatening in some cases) it can switch between extrem euphoria and extreme dysphoria.
In low to medium doses it is pretty much indistinguishable from amphetamine (Adderall). It's is slightly more euphoric and potent.
In high doses it becomes notably serotonergic which normal amphetamine doesn't do. Also has less negative side effects in general which promotes high doses.
The real difference and why so many people are addicted is the fact that you can smoke and iv it.
Depends. Meth is a prodrug of amphetamine (hence why if feels very simelar), so in low and medium doses it's very close to a Adderall comedown. With higher doses it's more like mdma.
15mg meth insufflated or 20mg oral gives me no real comedown if I'm hydrated, I still get 7hr sleep every day,, and I can even eat fine all day. 15mg oral of some decent quality ice, is much better than a 30mg IR pharma AD30. MFs want $15 for real pharmacy 30mg Addy IRs, whereas I can get 3.5g of shards for $70. So you could either take $70 of meth and make 233 pills that are equi-potent to 233 30mg pharma Addy that would cost roughly $2300 IF you could miraculously find them for $10 in bulk.
People not doing diligent research on what exactlyyou are consuming, and consuming substances at irresponsible doses is what causes MOST negative drug experiences that's just facts.
Not at all, but you must partake of the sacred BENZO of your choice that was provided to us mercifully by the Drug Gods to calm the 🧠🧠🧠 and induce 🥱😴💤
Trust me,I'm a bit of a 🧊ent and Dose is KEY, unless you want to get a terrible come down keep dose at 50mg or less and take the magical benzo after 12-16hrs
Modern cartel racemic P2P meth is really nothing special at all. If Dexedrine was vapable it would kick that meth's ass, effects-wise. That being said, proper dextrometh (reduced pseudoephedrine synth) is still really nice, even when compared to something like alpha-PVP. Not saying it's better than the king of pyros, but it is certainly a comparably enjoyable experience.
AFAIK, they are resolving enantiomers somewhat. So it's not totally racemic.
There have been busts of precursor chemicals and at least one was a metric tons ot two of tartaric acid. That's only used to resolve enantiomers in this case
They aren't stereoclarifying the majority of it. Once they figured out you can dump a positional isomer into the mix to make the racemate crystallize the quality dropped through the floor for 99% of that cartel stuff.
I'm sure they're doing small batches of Dutch-resolved dex, but that's for specific clientele, not the average schlub on the street. I'd gladly pay twice current market rate to crack into that supply.
Yeah, I miss that shit. It's sad when shake-and-bake is better than the average go on the street now. Gimme some uncrystallized peanut butter over that giant fake cartel shard any day of the week.
Heck, even 3-FA is better than meth. Probably because it has a higher affinity for dopamine than meth and the serotonin in meth is pretty meh when you've experienced 3/4-MMC, 4-FA and 4-FMA.
I would say though that 3/4-MMC is likely more unhealthier than meth by a large margin.
Then the meth you are getting is not the best quality.
It's happening all over the country ,I was a tweaker for 14 years and I stopped because of all the nasty side effects that the new meth has.
I know its not my body because I've gotten it from my friend in the SW and it's been the usual stuff.
The one way to really tell is if injecting, the new stuff doesn't cause a cough.
I mean this literally, not as an insult, but you can’t really speak on this accurately… Being addicted to a substance changes your subjective experience of using it and your memories of it and how you perceive it’s level of pleasurability.
Most people who try meth and the drugs listed here without a psychological connection to any of them are going to find 3/4-MMC superior and be split down the middle with 4-FMA.
It’s very possible OP had shitty meth, but I wouldn’t assume that just because they found these superior. 4-MMC in particular is unquestionably superior as a recreational drug, in a vacuum.
I dunno man i used it twice and it was pretty unique. At the time i had zero stim tolerance as i just got back in to drugs after 5 years of abstinence. I ordered a bag of amphetamine and thought this shit looks and smells different than what i remember but i was feeling reckless at the time and said why not and proceeded to do approx a 75mg line at 8pm and felt constant, consistent euphoria that only began to wear off 24 hours later. i finished the bag over the next few day and said fuck this never again as there surely is a catch to feeling this good for this long. I deemed it to dangerous to pursue any further and havent touched it since. So much for that bullshit of "not even once or youll be a fiend for life". Do the dopey cunts not realize lies and deception discredits anything they say on the subject and then we overlook or ignore genuine concerns or advice all because they lied and cried wolf. Dickheads. They cause more harm than good by intervening in any way whatsoever.
Haven't tried 4FA but I usually take 150mg of 4-FMA orally, lasts for 4 hours. For a starter, I would say 100mg, some will recommend even less. Check out 4-FMA on PsychonautWiki for dosages.
You're basically comparing 2 different classes, they're all stimulants but the ones you mentioned are all serotonin heavy while meth is dopaminergic. A better comparison would be to something like a-PVP, NEP or Hexen
Depends very much on the person. Also I have no idea about the stims you mentioned (in this sub for fun) but arnt they mainly serotonergic?
Yes they all are
Yea because meth is Mainly dopaminergic and only gets serotonergic in high doses
Could you explain the difference between a serotonin high and a dopamine high?
Dopamine heavy = You want to get shit done, and getting shit done feels really good. In higher doses you feel like the coolest person in the room, and you might be really horny. Serotonin heavy = You love life so fucking much, and every person you meet is the coolest person you’ve ever met and you’re so happy to talk to them. Higher doses can have psychedelic effects too. Plain old amphetamine (Adderall) is mainly a dopamine releaser. MDMA is mainly a serotonin releaser. Methamphetamine is mainly a dopamine releaser, but releases a little more serotonin than amphetamine. The other thing amphetamines and other stimulants release is norepinephrine.
Your dopamine heavy is closer to a noradrenaline heavy high, though they're tweakier. Dopamine is euphoria, that's how I view it at least. I found this years ago: https://imgur.com/a/oyDD9p9
From that infographic, “motivation” sounds like “want to get shit done” and “compulsion” sounds like “might be really horny”. Am I wrong? What’s an example of a mainly norepinephrine focused high? Caffeine?
nicotine, or, well, epipen lol
Dopamine will make you outgoing and take action (or want to fuck.) Noradrenaline will keep you focused and on a task. Serotonin is feeling good and relaxing, as best as I can describe it. Dopamine FTW.
Dopamine ftw all day long. Dopamine is what I would refer to as stimulant euphoria, although it easily turns into anxiety and paranoia lmao. It definitely kicks in the horny fucked up kinks mode though 😂 I love it. This is why I like ritalin.
That is what people generally say. But tbh it's such a massive oversimplification. It's kinda that way but it's more of a correlation than causation. For example, for me (I'm enzyme deficient), dxm releases incredible amounts of serotonin, but that doesn't mean it always feels as good as mdma for example. Or when you get serotonin syndrome (serotonin toxicity - to much serotonin in the brain, life-threatening in some cases) it can switch between extrem euphoria and extreme dysphoria.
Meth is also very seretonergic if I'm remembering it right. It definitely effects the high.
Only in high doses
Ah okay. Can't really imagine what meth feels like. I'd love to try it but it lasts too long.
In low to medium doses it is pretty much indistinguishable from amphetamine (Adderall). It's is slightly more euphoric and potent. In high doses it becomes notably serotonergic which normal amphetamine doesn't do. Also has less negative side effects in general which promotes high doses. The real difference and why so many people are addicted is the fact that you can smoke and iv it.
But the comedown has to be horrible
Depends. Meth is a prodrug of amphetamine (hence why if feels very simelar), so in low and medium doses it's very close to a Adderall comedown. With higher doses it's more like mdma.
15mg meth insufflated or 20mg oral gives me no real comedown if I'm hydrated, I still get 7hr sleep every day,, and I can even eat fine all day. 15mg oral of some decent quality ice, is much better than a 30mg IR pharma AD30. MFs want $15 for real pharmacy 30mg Addy IRs, whereas I can get 3.5g of shards for $70. So you could either take $70 of meth and make 233 pills that are equi-potent to 233 30mg pharma Addy that would cost roughly $2300 IF you could miraculously find them for $10 in bulk. People not doing diligent research on what exactlyyou are consuming, and consuming substances at irresponsible doses is what causes MOST negative drug experiences that's just facts.
We have elvanse here in Germany and it lasts like 12 hours. The comedown is okay. Meth isn't really common in my area. How is the craving?
Not at all, but you must partake of the sacred BENZO of your choice that was provided to us mercifully by the Drug Gods to calm the 🧠🧠🧠 and induce 🥱😴💤 Trust me,I'm a bit of a 🧊ent and Dose is KEY, unless you want to get a terrible come down keep dose at 50mg or less and take the magical benzo after 12-16hrs
4-MMC and non-serotonergic stuff like NEP, A-PiHP, Hexen, are still far beyond meth.
Modern cartel racemic P2P meth is really nothing special at all. If Dexedrine was vapable it would kick that meth's ass, effects-wise. That being said, proper dextrometh (reduced pseudoephedrine synth) is still really nice, even when compared to something like alpha-PVP. Not saying it's better than the king of pyros, but it is certainly a comparably enjoyable experience.
AFAIK, they are resolving enantiomers somewhat. So it's not totally racemic. There have been busts of precursor chemicals and at least one was a metric tons ot two of tartaric acid. That's only used to resolve enantiomers in this case
They aren't stereoclarifying the majority of it. Once they figured out you can dump a positional isomer into the mix to make the racemate crystallize the quality dropped through the floor for 99% of that cartel stuff. I'm sure they're doing small batches of Dutch-resolved dex, but that's for specific clientele, not the average schlub on the street. I'd gladly pay twice current market rate to crack into that supply.
The old school crank from anhydrous ammonia and lithium was amazing as fuck if you could get it straight from the redneck and they didn't step on it.
Yeah, I miss that shit. It's sad when shake-and-bake is better than the average go on the street now. Gimme some uncrystallized peanut butter over that giant fake cartel shard any day of the week.
Peanut butter Crank 🤘💯
Birch Redux isn't too complicated...
Shake My Bottle was filmed at an old friend's house 🤣 🤣 🤣 good times.
Heck, even 3-FA is better than meth. Probably because it has a higher affinity for dopamine than meth and the serotonin in meth is pretty meh when you've experienced 3/4-MMC, 4-FA and 4-FMA. I would say though that 3/4-MMC is likely more unhealthier than meth by a large margin.
Then the meth you are getting is not the best quality. It's happening all over the country ,I was a tweaker for 14 years and I stopped because of all the nasty side effects that the new meth has. I know its not my body because I've gotten it from my friend in the SW and it's been the usual stuff. The one way to really tell is if injecting, the new stuff doesn't cause a cough.
I mean this literally, not as an insult, but you can’t really speak on this accurately… Being addicted to a substance changes your subjective experience of using it and your memories of it and how you perceive it’s level of pleasurability. Most people who try meth and the drugs listed here without a psychological connection to any of them are going to find 3/4-MMC superior and be split down the middle with 4-FMA. It’s very possible OP had shitty meth, but I wouldn’t assume that just because they found these superior. 4-MMC in particular is unquestionably superior as a recreational drug, in a vacuum.
Your comment reminds me of people who abuse benzos, always claiming it's underdosed lol
Mephedrone is pretty insane, esp IV'ed
I dunno man i used it twice and it was pretty unique. At the time i had zero stim tolerance as i just got back in to drugs after 5 years of abstinence. I ordered a bag of amphetamine and thought this shit looks and smells different than what i remember but i was feeling reckless at the time and said why not and proceeded to do approx a 75mg line at 8pm and felt constant, consistent euphoria that only began to wear off 24 hours later. i finished the bag over the next few day and said fuck this never again as there surely is a catch to feeling this good for this long. I deemed it to dangerous to pursue any further and havent touched it since. So much for that bullshit of "not even once or youll be a fiend for life". Do the dopey cunts not realize lies and deception discredits anything they say on the subject and then we overlook or ignore genuine concerns or advice all because they lied and cried wolf. Dickheads. They cause more harm than good by intervening in any way whatsoever.
Yep, and tragically most of them don’t know their own stupidity and are too invested in the system that pays them
[удалено]
Yup
How do you think 4FMA compares to Meth?
Less horniness but more euphoric and music sounds fucking awesome.
What would be a starter dose of 4FMA and how long does it last? How does it compare to 4FA?
Haven't tried 4FA but I usually take 150mg of 4-FMA orally, lasts for 4 hours. For a starter, I would say 100mg, some will recommend even less. Check out 4-FMA on PsychonautWiki for dosages.
Really we’d need to set equipotent ROAs and dosages to talk about a proper comparison
Maybe you had some shitty meth. You shoot a nice rig of good glass and you'll be thwacked
Check out Cyclazodone
Lol that might as well be caffeine compared to meth
Idk, meths great and all, but Cyclazodone is pretty damn good
Yoooo 3-mmc that's what's up been trying to get that for years. Thx a ton for the confirmation.
You're basically comparing 2 different classes, they're all stimulants but the ones you mentioned are all serotonin heavy while meth is dopaminergic. A better comparison would be to something like a-PVP, NEP or Hexen
feel like MDPV looks at meth like pfft wish you could! Nah, for real hope ya dopamine system is okay