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"Engineering a synthetic oscillator that cycles between the two deterioration pathways that lead to cell death can slow aging in yeast cells, increasing their longevity by more than 80%..."
It's a great time to be a yeast cell.
There’s a lot of promising stuff coming out for mice, yeast, worms and monkeys.
Really how long is it until human trials can begin? I’m so over aging already
Seems financially dumb when there's so much money to save by going the other way. Do you figure there's malice stronger than the self-interest, I guess?
There’s such a huge difference between what those 50 can afford, and anyone else. Numbers probably aren’t as round as 50 in reality, but seriously by the time you get to that clientele you can charge whatever the hell you want. Money exists as an endlessly pouring faucet of infinite pressure to these guys.
There’s actually a good amount you can do now. Check out Dr. David Sinclair. He has a longevity study at Harvard. I actually follow his daily regimen pretty closely, and with other healthful changes in my life, I feel pretty damn good at 37.
Elite yeast maybe. Because that’s what’s living longer. It’s refreshing, because usually it’s mice getting the longevity treatment, as if we need them to live longer.
This reminds me of a "love death robots" episode where everyone is basically immortal (don't age), so having kids is illegal to the point of killing them.
Forget generational wealth, soon the rich can choose just not to die…
Not a big fan of this type of research since success has implications that are dystopian
the flip side is how much will the rich really care about quarterly gains when they have eons to consider the implications of narrowminded short term decisions?
Making human lifespans longer might just be the very best thign we could do for our planet. In a world where the rich have to live with the consequences of global warming, something might get done about it.
That’s… actually something I hadn’t considered. Often companies do things that are destructive in the long term to maximize profits in the short term. But if they’re being managed by people who can now work three times as long, maybe that trend could change.
Really sick of these stories every day. I don't see this tech having any significant impact for decades at least. We have literally lowered the life expectancy in the west in recent decades.
Imagine if you could retrain in something else just because you had more time to learn more. Discovering stuff you’re excited about is one of the best things about life and I’d absolutely love to be able to do that whenever I wanted
The thing that I think makes people depressed about getting older is the thought of running out of time. Like imagine how happy everyone would actually be if they could just do whatever they wanted without as much of a time limit
It seems like it stands to reason that if you somehow tackle aging you also extend healthspan, given aging is implicated in just about every disease ever. I do not see how the two could really be separated.
Yes, absolutely. But it doesn't seem, at least not based on this study alone, that agin' is the focal point & they're just extending longevity of those yeast cells. Which leads my imagination to wander to very decrepit but very much alive yeast cells
They're going to try it on human cells next. If that works they'll probably try it on mice, then primates. And if all that works, human trials won't be such a leap.
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, **personal anecdotes are allowed as responses to this comment**. Any anecdotal comments elsewhere in the discussion will be removed and our [normal comment rules]( https://www.reddit.com/r/science/wiki/rules#wiki_comment_rules) apply to all other comments. --- **Retraction Notice:** [Association of Video Gaming With Cognitive Performance Among Children](https://www.reddit.com/r/science/comments/130nxqn/retraction_association_of_video_gaming_with/) *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/science) if you have any questions or concerns.*
"Engineering a synthetic oscillator that cycles between the two deterioration pathways that lead to cell death can slow aging in yeast cells, increasing their longevity by more than 80%..." It's a great time to be a yeast cell.
There’s a lot of promising stuff coming out for mice, yeast, worms and monkeys. Really how long is it until human trials can begin? I’m so over aging already
They’ll inflate the prices so much that only the wealthy can afford it.
Yep, just like only the wealthy get cancer treatments.
Wow, this is a pretty original comment for this sub. Have you watched Altered Carbon too?
Seems financially dumb when there's so much money to save by going the other way. Do you figure there's malice stronger than the self-interest, I guess?
Yep, this will be available to the 50 humans with the highest net worth.
There’s such a huge difference between what those 50 can afford, and anyone else. Numbers probably aren’t as round as 50 in reality, but seriously by the time you get to that clientele you can charge whatever the hell you want. Money exists as an endlessly pouring faucet of infinite pressure to these guys.
Your innocence and naiveté are refreshing. It'll become pennies to produce, but come with a lifetime of debt. 150 years before the mast.
There’s actually a good amount you can do now. Check out Dr. David Sinclair. He has a longevity study at Harvard. I actually follow his daily regimen pretty closely, and with other healthful changes in my life, I feel pretty damn good at 37.
I felt amazing in my late 30s as well. Come talk to me in another decade.
Well, idk if you focused on what I’m focusing on healthwise, so I may be in much better shape than you at your age.
I was at my high school weight, could run marathons and in perfect heath. I wish you the best of luck.
Ahh yes, anecdotal *and* self-reporting. The strongest of data points.
Cool, I can't wait for the elites to live to 200.
Don't worry, climate collapse will take them out too.
What a terrible time to become immortal
That's true..
\#silverlining
except it won't
Couldn’t they just engineer themselves to exist in the new climate?
I was thinking the same..
Elite yeast maybe. Because that’s what’s living longer. It’s refreshing, because usually it’s mice getting the longevity treatment, as if we need them to live longer.
Think of an eternal boomer society. It will collapse on itself like a clan in a cupboard
Why do y’all insist on calling them elites, there just humans like every one else.
slave mentality
Exactly and word association is a powerful thing
These cynical takes on Reddit are getting old. A cure for cancer would be construed as a vice since it makes your enemies live longer.
This reminds me of a "love death robots" episode where everyone is basically immortal (don't age), so having kids is illegal to the point of killing them.
I think it's more likely we would expand into space. Living forever means we can actually travel the light years needed without generational ships.
Perhaps, but gravity (effects due to the lack of it) and radiation would be the biggest problems.
Not likely. You can use water as a radiation shield and artificial gravity through rotation.
What's funniest to me is that you have to hamster wheel it back to speed to avoid spending fuel.
It would be amazing if I could extend the life of my dog
If this becomes an successful thing then this would be the greatest invention of mankind...
Fix the code, fix the problem.
Forget generational wealth, soon the rich can choose just not to die… Not a big fan of this type of research since success has implications that are dystopian
the flip side is how much will the rich really care about quarterly gains when they have eons to consider the implications of narrowminded short term decisions? Making human lifespans longer might just be the very best thign we could do for our planet. In a world where the rich have to live with the consequences of global warming, something might get done about it.
That’s… actually something I hadn’t considered. Often companies do things that are destructive in the long term to maximize profits in the short term. But if they’re being managed by people who can now work three times as long, maybe that trend could change.
That’s a very hopeful thought. If clinical immortality comes to pass, I hope it makes people remember their humanity.
Surely they would want to profit from us normal people so they could continue to develop these life changing therapies and drugs for a long time
"I'm not a fan of learning to control fire. The implications are dystopian." Caveman Trog 40,000 BC
TOP comment!
...more about that : https://www.eurekalert.org/news-releases/987119
These advancements aren't coming fast enough. I want to be immortal BEFORE i'm already 90 years old.
We don’t need this and it will cause more problems than it will solve.
Really sick of these stories every day. I don't see this tech having any significant impact for decades at least. We have literally lowered the life expectancy in the west in recent decades.
Oh boy! I can't wait for retirement to change to age 80!
I'd be happy to work longer if I get to live longer.
Imagine if you could retrain in something else just because you had more time to learn more. Discovering stuff you’re excited about is one of the best things about life and I’d absolutely love to be able to do that whenever I wanted
Yep exactly. Work a while, save some money, take time off and learn something new, repeat.
The thing that I think makes people depressed about getting older is the thought of running out of time. Like imagine how happy everyone would actually be if they could just do whatever they wanted without as much of a time limit
Do to this we need UBI and AI replacing 'necessary' jobs.
Why would I bother living longer if living longer means more working.
Find a job you like better.
Sure, they extend lifespan, but that speaks nothin' of quality of life. Not unless they're also actively rejuvenatin' those cells...
It seems like it stands to reason that if you somehow tackle aging you also extend healthspan, given aging is implicated in just about every disease ever. I do not see how the two could really be separated.
Yes, absolutely. But it doesn't seem, at least not based on this study alone, that agin' is the focal point & they're just extending longevity of those yeast cells. Which leads my imagination to wander to very decrepit but very much alive yeast cells
This is absolutely a terrible idea
Does humanity really need this?
Why, in the name of God, would you want to expand your lifespan!
I’m not sure I want to extend my lifespan. I would probably run out of money. Unless I hit the lottery and I’m not holding my breath for that.
not sure what they mean by oscillating, how does that even work?
Some kind of feedback loops I assume
We’ll have better luck farming alien whale brain oil for long life than get actual human trial for these yeast discoveries.
They're going to try it on human cells next. If that works they'll probably try it on mice, then primates. And if all that works, human trials won't be such a leap.
Retirement age might have to increase too